Tubular adenoma of the urinary tract

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Tubular adenoma of the urinary tract
Diagnosis in short

Tubular adenoma of the urinary tract. H&E stain.
LM glands with pseudostratified hyperchromatic nuclei without maturation to the surface
LM DDx in situ adenocarcinoma of the urinary bladder, adenocarcinoma of the urinary bladder, metastatic adenocarcinoma
IHC CK20 +ve, CDX2 +ve, CK7 -ve, GATA3 -ve
Site urinary tract - urinary bladder, ureter, renal pelvis
Prevalence uncommon
Prognosis benign

Tubular adenoma of the urinary tract is a very rare lesion of the urinary tract that looks like a tubular adenoma of the gastrointestinal tract.[1]

General

  • Very rare.

Note:

  • Villous adenoma of the urinary tract[2][3] and tubulovillous adenoma of the urinary tract[4] are also reported.

Microscopic

Features:

  • Glands with pseudostratified hyperchromatic nuclei without maturation to the surface.

DDx:

Images

  • TAUT - very low mag. (WC)

  • TAUT - low mag. (WC)

  • TAUT - intermed. mag. (WC)

  • TAUT - high mag. (WC)

IHC

Features:[1]

See also

References

  1. ↑ 1.0 1.1 Kao, CS.; Epstein, JI. (Sep 2013). "Tubular adenoma of the urinary tract: a newly described entity.". Hum Pathol 44 (9): 1890-4. doi:10.1016/j.humpath.2013.02.017. PMID 23664485.
  2. ↑ Seibel, JL.; Prasad, S.; Weiss, RE.; Bancila, E.; Epstein, JI. (Feb 2002). "Villous adenoma of the urinary tract: a lesion frequently associated with malignancy.". Hum Pathol 33 (2): 236-41. PMID 11957151.
  3. ↑ Ratanarapee, S.; Uiprasertkul, M.; Pradniwat, K.; Soontrapa, S. (Nov 2010). "Villous adenoma of the urinary bladder: a case report.". J Med Assoc Thai 93 (11): 1336-9. PMID 21114216.
  4. ↑ Adegboyega, PA.; Adesokan, A. (Jul 1999). "Tubulovillous adenoma of the urinary bladder.". Mod Pathol 12 (7): 735-8. PMID 10430279.
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