Peliosis hepatis

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Peliosis hepatis is a type of medical liver disease.

General

  • Prevalence - very rare.[1]
  • Rarely biopsied.
  • May cause hemoperitoneum.[1][2]
  • Etiology - unknown.[3]

Associated with:

  • Infections.
  • Malignancy.
  • Other stuff.

Clinical DDx:

Microscopic

Features:

  • Multiple small cysts[1] lined by endothelium.
    • Usually incomplete.
  • Blood.

Images

A. Hemorrhage at left end, dilated sinusoids elsewhere (20X).
B. Ramifying dilated sinusoidal spaces (100X).
C. PAS with diastase shows flat lining (400X).
D. Necrotic hepatocytes in cords, presumably due to pressure (400X).
Peliosis hepatis. A. Hemorrhage at left end, dilated sinusoids elsewhere. B. Ramifying dilated sinusoidal spaces. C. PAS with diastase shows flat lining. D. Necrotic hepatocytes in cords, presumably due to pressure.

See also

References

  1. ↑ 1.0 1.1 1.2 Crocetti, D.; Palmieri, A.; Pedullà, G.; Pasta, V.; D'Orazi, V.; Grazi, GL. (Dec 2015). "Peliosis hepatis: Personal experience and literature review.". World J Gastroenterol 21 (46): 13188-94. doi:10.3748/wjg.v21.i46.13188. PMID 26675327.
  2. ↑ Buelow, B.; Otjen, J.; Sabath, AP.; Harruff, RC. (Dec 2012). "Peliosis hepatis presenting as liver rupture in a vulnerable adult: a case report.". Am J Forensic Med Pathol 33 (4): 307-10. doi:10.1097/PAF.0b013e31823a8b38. PMID 22104329.
  3. ↑ 3.0 3.1 Dai, W.; Zhong, D. (Oct 2013). "Peliosis hepatis mimicking cancer: A case report.". Oncol Lett 6 (4): 960-962. doi:10.3892/ol.2013.1479. PMID 24137445.
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