Red blood cell
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The red blood cell, abbreviated RBC, is the carrier of oxygen to tissue. It is seen daily by pathologists.
It is approximately 8 micrometers in diameter.[1]
Precursors
Reticulocyte
The direct precursor to the RBC is the reticulocyte.
Image:
Normoblast
Normoblasts are the nucleated precursors of RBCs.
Images:
Conditions with RBCs
Sickle cell disease
Main article: Sickle cell disease
Anemia
Main article: Anemia
Hemophagocytic syndrome
Main article: Hemophagocytic syndrome
- Macrophages eat whole RBCs.
Myospherulosis
General
- Foreign body-type granulomatous reaction to lipid-containing material and blood.[2][3]
- Rare.[4]
Etiology:
- Exposure to dying fat,[2] e.g. fat necrosis of the breast.
- Malignancy, e.g. renal cell carcinoma.[5]
Microscopic
Features:
- Phagocytosed RBCs.
- Round aggregates of red blood cells ~10-20 RBCs in diameter (80-160 micrometers).
See also
References
- ↑ URL: http://www.wisegeek.com/how-large-is-a-micrometer.htm. Accessed on: 17 January 2011.
- ↑ 2.0 2.1 2.2 Godbersen, GS.; Kleeberg, J.; Lüttges, J.; Werner, JA. (Sep 1995). "[Spherulocytosis (myospherulosis) of the paranasal sinuses].". HNO 43 (9): 552-5. PMID 7591868.
- ↑ Fisher, SC.; Horning, GM.; Hellstein, JW. (Dec 2001). "Myospherulosis complicating cortical block grafting: a case report.". J Periodontol 72 (12): 1755-9. doi:10.1902/jop.2001.72.12.1755. PMID 11811513.
- ↑ Sarkar, S.; Gangane, N.; Sharma, S. (Oct 1998). "Myospherulosis of maxillary sinus--a case report with review of literature.". Indian J Pathol Microbiol 41 (4): 491-3. PMID 9866916.
- ↑ Chau, KY.; Pretorius, JM.; Stewart, AW. (Oct 2000). "Myospherulosis in renal cell carcinoma.". Arch Pathol Lab Med 124 (10): 1476-9. doi:10.1043/0003-9985(2000)1241476:MIRCC2.0.CO;2. PMID 11035579.