Extranodal NK/T-cell lymphoma, nasal type
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Extranodal NK/T-cell lymphoma, nasal type (abbreviated ENKTCL), also known as extranodal natural kill lymphoma (abbreviated ENKL) and angiocentric lymphoma, is a rare type of lymphoma.
General
Microscopic
Features:
- Atypical lymphoid cells:
- Nucleoli.
- Nuclear pleomorphism.
- Cells centered around vessels (angiocentric).
- May destroy small and medium sized arterioles.
Images:
- Extranodal NK/T-cell lymphoma, nasal type - case 1 - several images (upmc.edu).
- Extranodal NK/T-cell lymphoma, nasal type - case 2 - several images (upmc.edu).
IHC
Features:[3]
- CD2 +ve.
- CD3 +ve (cytoplasmic).
- CD56 +ve.
Others:[4]
- TIA-1 +ve.
- CD7 +ve.
- EBER +ve.
See also
References
- ↑ Suzuki, R.; Takeuchi, K.; Ohshima, K.; Nakamura, S. (Jun 2008). "Extranodal NK/T-cell lymphoma: diagnosis and treatment cues.". Hematol Oncol 26 (2): 66-72. doi:10.1002/hon.847. PMID 18283711.
- ↑ Tse, E.; Kwong, YL. (Jun 2013). "How I treat NK/T-cell lymphomas.". Blood 121 (25): 4997-5005. doi:10.1182/blood-2013-01-453233. PMID 23652805.
- ↑ Al-Hakeem, DA.; Fedele, S.; Carlos, R.; Porter, S. (Jan 2007). "Extranodal NK/T-cell lymphoma, nasal type.". Oral Oncol 43 (1): 4-14. doi:10.1016/j.oraloncology.2006.03.011. PMID 17064952.
- ↑ URL: http://path.upmc.edu/cases/case310.html. Accessed on: 14 January 2012.