Extranodal extension

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Extranodal extension, abbreviated ENE, is extension of tumour from a lymph node metastasis to tissue outside of the lymph node. A precise consensus definition does not exist.[1]

ENE is important in cancer staging and a poor prognosticator.

See also

References

  1. ↑ Abdel-Halim CN, Rosenberg T, Larsen SR, Høilund-Carlsen PF, Sørensen JA, Rohde M, Godballe C (June 2021). "Histopathological Definitions of Extranodal Extension: A Systematic Review". Head Neck Pathol 15 (2): 599–607. doi:10.1007/s12105-020-01221-4. PMC 8134648. PMID 32918710. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134648/.
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