Diffuse panbronchiolitis

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Diffuse panbronchiolitis, abbreviated DPB, is a rare lung disease.

General

  • Rare lung disease predominantly found among asians.[1]
  • Has been likened to cystic fibrosis - but doesn't really share any features with it.

Gross

Features:[1]

  • Bronchiectasis.
  • Hyperinflation.
  • Small nodules (~2-3 mm) around the small airways.
  • Diffuse involvement of both lungs.

Microscopic

Features:[1]

  • Transmural inflammation of bronchioles - esp. respiratory bronchioles.
    • Lymphocytes, plasma cells, histiocytes.
  • Neutrophils within the airway.

Images

See also

References

  1. 1.0 1.1 1.2 Poletti, V.; Casoni, G.; Chilosi, M.; Zompatori, M. (Oct 2006). "Diffuse panbronchiolitis.". Eur Respir J 28 (4): 862-71. doi:10.1183/09031936.06.00131805. PMID 17012632.