Difference between revisions of "Walthard cell rest"

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#redirect [[gynecologic pathology#Walthard_cell_rest]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Walthard cell rest - very low mag.jpg
| Width      =
| Caption    = A cystic Walthard cell rest of the [[fallopian tube]]. [[H&E stain]].
| Synonyms  =
| Micro      = collection of eosinophilic (i.e. pink) cuboidal cells - usually solid, may be cystic; elliptical nucleus with single groove along major axis - "coffee bean" nucleus
| Subtypes  =
| LMDDx      = [[Brenner tumour]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Site      = [[Fallopian tube]], [[testis]]
| Assdx      =
| Syndromes  = none
| Clinicalhx =
| Signs      = none
| Symptoms  =
| Prevalence = common
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    =
| Tx        = none
}}
'''Walthard cell rest''', also '''Walthard cell nest''', is a benign finding often seen in [[gynecologic pathology]].
 
==General==
*Benign.
*Typically an incidental finding.
*May be found in the [[testis]].<ref name=pmid15502808>{{cite journal |author=Amin MB |title=Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors |journal=Mod. Pathol. |volume=18 Suppl 2 |issue= |pages=S131–45 |year=2005 |month=February |pmid=15502808 |doi=10.1038/modpathol.3800314 |url=}}</ref>
 
===Epidemiology===
*Thought to be related to [[Brenner tumour]].
 
==Microscopic==
Features:<ref name=Ref_GP332>{{Ref_GP|332}}</ref>
*Collection of eosinophilic (i.e. pink) cuboidal cells; usually solid, may be cystic.
*Elliptical nucleus with single groove along major axis; [[coffee bean nucleus|"coffee bean" nucleus]] -- '''key feature'''.
 
Location:
*Usually in soft tissue of the uterine tube.
 
DDx:
*[[Brenner tumour]] - consist of (multiple) nests with a surrounding fibromatous stroma.<ref name=pmid25281026>{{Cite journal  | last1 = Roma | first1 = AA. | last2 = Masand | first2 = RP. | title = Ovarian Brenner tumors and Walthard nests: a histologic and immunohistochemical study. | journal = Hum Pathol | volume = 45 | issue = 12 | pages = 2417-22 | month = Dec | year = 2014 | doi = 10.1016/j.humpath.2014.08.003 | PMID = 25281026 }}</ref>
 
===Images===
====Fallopian tube====
<gallery>
Image:Walthard cell rest - very high mag.jpg | WCR - very high mag.
Image:Walthard cell rest - high mag.jpg | WCR - high mag.
Image:Walthard cell rest - intermed mag.jpg | WCR - intermed. mag.
Image:Walthard cell rest - low mag.jpg | WCR - low mag.
Image:Walthard cell rest - very low mag.jpg | WCR - very low mag.
</gallery>
 
====Testis====
<gallery>
Image:Walthard cell rest testis -- low mag.jpg | Low mag.
Image:Walthard cell rest testis -- intermed mag.jpg | Intermed. mag.
Image:Walthard cell rest testis -- high mag.jpg | High mag.
Image:Walthard cell rest testis -- very high mag.jpg | Very high mag.
</gallery>
 
==See also==
*[[Gynecologic pathology]].
*[[Fallopian tube]].
 
==References==
{{Reflist|1}}
 
[[Category:Gynecologic pathology]]

Latest revision as of 19:23, 7 March 2016

Walthard cell rest
Diagnosis in short

A cystic Walthard cell rest of the fallopian tube. H&E stain.
LM collection of eosinophilic (i.e. pink) cuboidal cells - usually solid, may be cystic; elliptical nucleus with single groove along major axis - "coffee bean" nucleus
LM DDx Brenner tumour
Site Fallopian tube, testis
Syndromes none
Signs none
Prevalence common
Prognosis benign
Treatment none

Walthard cell rest, also Walthard cell nest, is a benign finding often seen in gynecologic pathology.

General

  • Benign.
  • Typically an incidental finding.
  • May be found in the testis.[1]

Epidemiology

Microscopic

Features:[2]

  • Collection of eosinophilic (i.e. pink) cuboidal cells; usually solid, may be cystic.
  • Elliptical nucleus with single groove along major axis; "coffee bean" nucleus -- key feature.

Location:

  • Usually in soft tissue of the uterine tube.

DDx:

  • Brenner tumour - consist of (multiple) nests with a surrounding fibromatous stroma.[3]

Images

Fallopian tube

  • WCR - very high mag.

  • WCR - high mag.

  • WCR - intermed. mag.

  • WCR - low mag.

  • WCR - very low mag.

Testis

  • Low mag.

  • Intermed. mag.

  • High mag.

  • Very high mag.

See also

References

  1. ↑ Amin MB (February 2005). "Selected other problematic testicular and paratesticular lesions: rete testis neoplasms and pseudotumors, mesothelial lesions and secondary tumors". Mod. Pathol. 18 Suppl 2: S131–45. doi:10.1038/modpathol.3800314. PMID 15502808.
  2. ↑ Nucci, Marisa R.; Oliva, Esther (2009). Gynecologic Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 332. ISBN 978-0443069208.
  3. ↑ Roma, AA.; Masand, RP. (Dec 2014). "Ovarian Brenner tumors and Walthard nests: a histologic and immunohistochemical study.". Hum Pathol 45 (12): 2417-22. doi:10.1016/j.humpath.2014.08.003. PMID 25281026.
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