Vocal cord nodule

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Vocal cord nodule, also vocal cord polyp and singer's nodule, is a benign pathology of the head and neck.

General

  • Benign.
  • AKA singer's nodule.
  • Etiology: overuse, mechanical trauma (?).

Microscopic

Features:[1]

  • Early:
    1. Edema.
    2. Fibroblasts proliferation.
  • Late:
    1. Subepithelial hyaline / stromal hyaline.
    2. Blood vessels - dilated.

Notes:

  • No inflammation.

DDx:[2]

Images

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VOCAL CORD LESION, EXCISION:
- STRATIFIED SQUAMOUS EPITHELIUM WITH PARAKERATOSIS AND STROMA EDEMA, CONSISTENT
  WITH BENIGN VOCAL CORD NODULE OR POLYP.
- NEGATIVE FOR MALIGNANCY.
VOCAL CORD LESION, EXCISION:
- STRATIFIED SQUAMOUS EPITHELIUM WITH PARAKERATOSIS AND SUBEPITHELIAL 
  HYALINE MATERIAL, CONSISTENT WITH WITH VOCAL CORD NODULE OR POLYP.
- NEGATIVE FOR MALIGNANCY.

See also

References

  1. URL: http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970310-2. Accessed on: 4 February 2011.
  2. Thompson, Lester D. R. (2006). Head and Neck Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 9. ISBN 978-0443069604.
  3. Abdou, AG.; Asaad, NY. (Oct 2012). "Rheumatoid nodule of the vocal cord.". Int J Surg Pathol 20 (5): 481-2. doi:10.1177/1066896912448426. PMID 22674917.