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Difference between revisions of "Vocal cord nodule"
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'''Vocal cord nodule''', also '''vocal cord polyp''' and '''singer's nodule''', is a benign pathology of the [[head and neck pathology|head and neck]]. | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | |||
| Image = Laryngeal_nodule_(1).jpg | |||
| Width = | |||
| Caption = Laryngeal nodule | |||
| Synonyms = singer's nodule, vocal fold nodule | |||
| Micro = early: edema, fibroblasts proliferation; late: subepithelial hyaline / stromal hyaline, blood vessels - dilated | |||
| Subtypes = | |||
| LMDDx = [[amyloidosis]], [[granular cell tumour]], spindle cell [[squamous cell carcinoma of the head and neck|squamous cell carcinoma]], myxoma, ductal-type cyst | |||
| Stains = [[congo red stain|congo red]] -ve | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[vocal cord]] - also see ''[[head and neck pathology]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = +/-hoarseness | |||
| Symptoms = | |||
| Prevalence = common | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Vocal cord nodule''', also '''vocal cord polyp''', '''vocal fold nodule''' and '''singer's nodule''', is a benign pathology of the [[head and neck pathology|head and neck]]. | |||
==General== | ==General== | ||
*Benign. | *Benign. | ||
*Etiology: overuse, "phonatory trauma"<ref name=pmid19730264>{{Cite journal | last1 = Karkos | first1 = PD. | last2 = McCormick | first2 = M. | title = The etiology of vocal fold nodules in adults. | journal = Curr Opin Otolaryngol Head Neck Surg | volume = 17 | issue = 6 | pages = 420-3 | month = Dec | year = 2009 | doi = 10.1097/MOO.0b013e328331a7f8 | PMID = 19730264 }}</ref> (yelling). | |||
*Etiology: overuse, | |||
Clinical: | |||
*Hoarseness.<ref name=pmid7502253>{{Cite journal | last1 = Müller | first1 = R. | title = [Hoarseness]. | journal = Ther Umsch | volume = 52 | issue = 11 | pages = 759-62 | month = Nov | year = 1995 | doi = | PMID = 7502253 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
| Line 21: | Line 54: | ||
*[[Amyloidosis]]. | *[[Amyloidosis]]. | ||
*[[Granular cell tumour]]. | *[[Granular cell tumour]]. | ||
*Spindle cell [[squamous cell carcinoma of the head and neck|squamous cell carcinoma]]. | *Spindle cell [[squamous cell carcinoma of the head and neck|squamous cell carcinoma]].<ref>{{Cite journal | last1 = Soylu | first1 = L. | last2 = Aydogan | first2 = B. | last3 = Tunali | first3 = N. | last4 = Ozsahinoglu | first4 = C. | title = Report of a rare case of vocal fold carcinoma that was obscured by a prominent vocal fold polyp. | journal = Ear Nose Throat J | volume = 78 | issue = 8 | pages = 601-2 | month = Aug | year = 1999 | doi = | PMID = 10485155 }}</ref> | ||
*Myxoma. | *Myxoma. | ||
*Ductal-type cyst. | *Ductal-type cyst. | ||
*[[Rheumatoid nodule]].<ref name=pmid22674917>{{Cite journal | last1 = Abdou | first1 = AG. | last2 = Asaad | first2 = NY. | title = Rheumatoid nodule of the vocal cord. | journal = Int J Surg Pathol | volume = 20 | issue = 5 | pages = 481-2 | month = Oct | year = 2012 | doi = 10.1177/1066896912448426 | PMID = 22674917 }}</ref> | |||
*[[Rheumatoid nodule]].<ref>{{Cite journal | last1 = Abdou | first1 = AG. | last2 = Asaad | first2 = NY. | title = Rheumatoid nodule of the vocal cord. | journal = Int J Surg Pathol | volume = 20 | issue = 5 | pages = 481-2 | month = Oct | year = 2012 | doi = 10.1177/1066896912448426 | PMID = 22674917 }}</ref> | |||
===Images=== | ===Images=== | ||
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==Sign out== | ==Sign out== | ||
<pre> | |||
Left Vocal Cord Polyp, Excision: | |||
- Stratified squamous epithelium with compact hyperkeratosis and stromal | |||
edema, consistent with benign vocal cord nodule or polyp. | |||
- NEGATIVE for malignancy. | |||
</pre> | |||
===Block letters=== | |||
<pre> | <pre> | ||
VOCAL CORD LESION, EXCISION: | VOCAL CORD LESION, EXCISION: | ||