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| LMDDx = [[prostate carcinoma]], metastatic [[adenocarcinoma]] | | LMDDx = [[prostate carcinoma]], metastatic [[adenocarcinoma]] | ||
| Stains = | | Stains = | ||
| IHC = PSA -ve, PSAP -ve | | IHC = [[PSA]] -ve, PSAP -ve | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
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**May "invade" vascular spaces - associated with elastosis (breakdown of elastic fibres<ref>URL: [http://medical-dictionary.thefreedictionary.com/elastosis http://medical-dictionary.thefreedictionary.com/elastosis]. Accessed on: 26 September 2011.</ref>). | **May "invade" vascular spaces - associated with elastosis (breakdown of elastic fibres<ref>URL: [http://medical-dictionary.thefreedictionary.com/elastosis http://medical-dictionary.thefreedictionary.com/elastosis]. Accessed on: 26 September 2011.</ref>). | ||
=== | ===Images=== | ||
<gallery> | <gallery> | ||
Image: Vasitis nodosa -11- intermed mag.jpg | VN - intermed. mag. (WC) | Image: Vasitis nodosa -11- intermed mag.jpg | VN - intermed. mag. (WC) | ||
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www: | www: | ||
*[http://www.webpathology.com/image.asp?n=11&Case=40 Vasitis nodosa (webpathology.com)]. | *[http://www.webpathology.com/image.asp?n=11&Case=40 Vasitis nodosa (webpathology.com)]. | ||
*[http://www.flickr.com/photos/lunarcaustic/6938362234/ Vasitis nodosa (flickr.com/lunar caustic)]. | |||
==IHC== | ==IHC== | ||
Features:<ref name=pmid10843416>{{Cite journal | last1 = Sakaki | first1 = M. | last2 = Hirokawa | first2 = M. | last3 = Horiguchi | first3 = H. | last4 = Wakatsuki | first4 = S. | last5 = Sano | first5 = T. | title = Vasitis nodosa: immunohistochemical findings--case report. | journal = APMIS | volume = 108 | issue = 4 | pages = 283-6 | month = Apr | year = 2000 | doi = | PMID = 10843416 }} | Features:<ref name=pmid10843416>{{Cite journal | last1 = Sakaki | first1 = M. | last2 = Hirokawa | first2 = M. | last3 = Horiguchi | first3 = H. | last4 = Wakatsuki | first4 = S. | last5 = Sano | first5 = T. | title = Vasitis nodosa: immunohistochemical findings--case report. | journal = APMIS | volume = 108 | issue = 4 | pages = 283-6 | month = Apr | year = 2000 | doi = | PMID = 10843416 }} | ||
</ref> | </ref> | ||
*PSA -ve. | *[[PSA]] -ve. | ||
*CK7 +ve | *[[CK7]] +ve | ||
*CK34betaE12 +ve. | *[[CK34betaE12]] +ve. | ||
*Vimentin +ve. | *Vimentin +ve. | ||
*CK19 +ve. | *CK19 +ve. | ||
Others: | Others: | ||
*PSAP -ve. | *[[PSAP]] -ve. | ||
==Sign out== | ==Sign out== | ||
<pre> | |||
Right Vas Deferens, Excision: | |||
- Vasitis nodosa. | |||
</pre> | |||
===Block letters=== | |||
<pre> | <pre> | ||
A. VAS DEFERENS WITH GRANULOMA, RIGHT, VASOVASOSTOMY: | A. VAS DEFERENS WITH GRANULOMA, RIGHT, VASOVASOSTOMY: | ||
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- COMPLETE CROSS SECTION OF VAS DEFERENS. | - COMPLETE CROSS SECTION OF VAS DEFERENS. | ||
</pre> | </pre> | ||
===Micro=== | |||
The sections show one unremarkable cross section of the vas deferens and several sections with a histocytic response at the external aspect of the vas deferens' muscle layers. The histocytes are aggregated and contains bland tubular structures with sperm. | |||
The tubular structures are POSITIVE for CK7 and CK34betaE12, and NEGATIVE for PSA. CD68 marks the histiocytes. | |||
==See also== | ==See also== |
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