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Difference between revisions of "Vascular thrombus"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Laminations_in_a_thrombus_-_high_mag.jpg | |||
| Width = | |||
| Caption = Thrombus with laminations. [[H&E stain]]. (WC/Nephron) | |||
| Synonyms = | |||
| Micro = layers consisting of platelets and fibrin - classically alternating with layers of RBCs (known as ''lines of Zahn'') | |||
| Subtypes = | |||
| LMDDx = tumour embolus, thromboembolus, fat embolism, amniotic fluid embolus, stasis (post-mortem) | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Staging = | |||
| Site = [[blood vessels]] | |||
| Assdx = atrial fibrillation, hypercoagulable states (e.g. cancer) | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = dependent on severity and location | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = D-dimer +ve | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = dependent on severity, location and underlying cause (if present) | |||
| Other = | |||
| ClinDDx = | |||
| Tx = clot buster, thrombectomy, anticoagulants | |||
}} | |||
'''Vascular thrombus''' is an uncommon [[pathology]] specimen that may be from an artery or vein. | '''Vascular thrombus''' is an uncommon [[pathology]] specimen that may be from an artery or vein. | ||
''Venous thrombus'' and ''arterial thrombus'' redirect here. | ''Venous thrombus'' and ''arterial thrombus'' redirect here. ''Pulmonary embolism'' is dealt with separately in the [[pulmonary embolism]] article. | ||
==General== | ==General== | ||
*Uncommonly comes to [[pathology]]. | *Uncommonly comes to [[pathology]]. | ||
| Line 10: | Line 42: | ||
*Endothelial injury. | *Endothelial injury. | ||
===Gross | Clinical: | ||
*D-dimer elevated.<ref name=pmid23784703>{{Cite journal | last1 = Kleinegris | first1 = MC. | last2 = ten Cate | first2 = H. | last3 = ten Cate-Hoek | first3 = AJ. | title = D-dimer as a marker for cardiovascular and arterial thrombotic events in patients with peripheral arterial disease. A systematic review. | journal = Thromb Haemost | volume = 110 | issue = 2 | pages = 233-43 | month = Aug | year = 2013 | doi = 10.1160/TH13-01-0032 | PMID = 23784703 }}</ref> | |||
==Gross== | |||
: See ''[[pulmonary embolism]]''. | : See ''[[pulmonary embolism]]''. | ||
Features: | Features: | ||
| Line 16: | Line 50: | ||
*Laminations. | *Laminations. | ||
==Microscopic== | |||
Features: | Features: | ||
*Layers consisting of platelets and fibrin. | *Layers consisting of platelets and fibrin. | ||
| Line 62: | Line 96: | ||
==References== | ==References== | ||
{{Reflist|1}} | {{Reflist|1}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Ditzels]] | [[Category:Ditzels]] | ||
[[Category:Cardiovascular pathology]] | |||