Difference between revisions of "Vascular malformations"

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#Venous angioma.
#Venous angioma.
#*Many small veins.
#*Many small veins.
#Caverous malformation.
#Cavernous hemangioma (Cavernoma).
#*Vessels are back-to-back (no intervening parenchyma).
#*Vessels are back-to-back (no intervening parenchyma).
#Capillary teleangiectasia
#*Small capillaries


Also see: ''[[Sturge-Weber syndrome]]''.
Also see: ''[[Sturge-Weber syndrome]]''.
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Image:
Image:
*[http://www.flickr.com/photos/11462589@N05/1125883661/in/photostream/ AVM (flickr.com)].
*[http://www.flickr.com/photos/11462589@N05/1125883661/in/photostream/ AVM (flickr.com)].
Clinical DDx:
*Melanocytic lesion.
*Other vascular lesions.


===Microscopic===
===Microscopic===
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**"Large" = ~ 0.5 mm (0.25-1.0 mm).
**"Large" = ~ 0.5 mm (0.25-1.0 mm).
***0.25 mm = ~ 31 RBC diameters across.
***0.25 mm = ~ 31 RBC diameters across.
Images:
*[[WC]]:
**[http://commons.wikimedia.org/wiki/File:Arteriovenous_malformation_-_brain_-_low_mag.jpg Cerebral AVM (WC)].
*www:
**[http://path.upmc.edu/cases/case123.html AVM - several images (upmc.edu)].


Notes:
Notes:
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*Arteries have a well-defined internal elastic lamina and an external elastic lamina (best seen on elastic trichrome).
*Arteries have a well-defined internal elastic lamina and an external elastic lamina (best seen on elastic trichrome).
**[[Vein]]s do not have an external elastic lamina and have a poorly developed/thin internal elastic lamina.
**[[Vein]]s do not have an external elastic lamina and have a poorly developed/thin internal elastic lamina.
DDx:
*Other vascular lesions.
====Images====
<gallery>
Image:Arteriovenous_malformation_-_brain_-_low_mag.jpg  | Cerebral AVM. (WC)
</gallery>
www:
*[http://path.upmc.edu/cases/case123.html AVM - several images (upmc.edu)].


===Sign out===
===Sign out===
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</pre>
</pre>


==Cavernous angioma==
 
==Cavernous hemangioma==
===General===
===General===
*Usually diagnosed by radiology.
*Usually diagnosed by radiology.
*Clinicians call it cavernoma.


===Microscopic===
===Microscopic===
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*Vessels back-to-back/little intervening parenchyma.
*Vessels back-to-back/little intervening parenchyma.
**Muscle is absent in the vessel walls - '''key feature'''.<ref>MUN. 23 November 2010.</ref>
**Muscle is absent in the vessel walls - '''key feature'''.<ref>MUN. 23 November 2010.</ref>
Images:
<gallery>
File:Cavernous hemangioma.jpg | Cavernous hemangioma (WC/Patho82).
File:Cavernous liver hemangioma - intermed mag.jpg | Cavernous hemangioma of the liver (WC).
</gallery>
==Venous angioma==
===General===
*Subcortical white matter.
*Most common vascular malformation found at autopsy.
===Gross===
*May look like petechial hemorrhages.
===Microscopy===
*Thin walled, dilated vascular channels.
*Lesions larger than capillary teleangiectasia.


==Cherry angioma==
==Cherry angioma==
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*[http://www.dermpathexpert.com/id30.html Cherry hemangioma (dermpathexpert.com)].
*[http://www.dermpathexpert.com/id30.html Cherry hemangioma (dermpathexpert.com)].
*[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/cherry_angioma_mid_power.jpg Cherry angioma (ucsf.edu)].<ref name=ucsf_ca>URL:: [http://missinglink.ucsf.edu/lm/DermatologyGlossary/cherry_angioma.html http://missinglink.ucsf.edu/lm/DermatologyGlossary/cherry_angioma.html]. Accessed on: 13 August 2012.</ref>
*[http://missinglink.ucsf.edu/lm/DermatologyGlossary/img/Dermatology%20Glossary/Glossary%20Histo%20Images/cherry_angioma_mid_power.jpg Cherry angioma (ucsf.edu)].<ref name=ucsf_ca>URL:: [http://missinglink.ucsf.edu/lm/DermatologyGlossary/cherry_angioma.html http://missinglink.ucsf.edu/lm/DermatologyGlossary/cherry_angioma.html]. Accessed on: 13 August 2012.</ref>
==Capillary teleangiectasia==
*Usually incidental finding at autopsy.
*Pons as predilection site.
===Microscopy===
*Many small, thin walled capillaries surrounded by normal brain.
*No hemorrhage.
Images:
<gallery>
File:Teleangiectasia brain.jpg | CNS teleangiectasia
</gallery>


==See also==
==See also==
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{{Reflist|2}}
{{Reflist|2}}


[[Category:Malformation]]
[[Category:Cardiovascular pathology]]
[[Category:Cardiovascular pathology]]
[[Category:Neuropathology]]
[[Category:Neuropathology]]
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