Difference between revisions of "Vascular disease"

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Vascular disease (view source)

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==Cystic medial degeneration==
==Cystic medial degeneration==
*[[AKA]] ''cystic medial necrosis''.<ref>URL: [http://emedicine.medscape.com/article/756835-overview http://emedicine.medscape.com/article/756835-overview]. Accessed on: 12 August 2010.</ref>
*[[AKA]] ''cystic medial necrosis''.<ref>URL: [http://emedicine.medscape.com/article/756835-overview http://emedicine.medscape.com/article/756835-overview]. Accessed on: 12 August 2010.</ref>
===General===
{{Main|Cystic medial degeneration}}
*Nonspecific finding - may be seen in a number of conditions.
 
Note about ''cystic medial necrosis'':
*Often ''not'' cystic and ''not'' necrotic.
 
===Microscopic===
Features:<ref>URL: [http://emedicine.medscape.com/article/756835-overview http://emedicine.medscape.com/article/756835-overview]. Accessed on: 12 August 2010.</ref><ref name=pmid17620463>{{cite journal |author=Ha HI, Seo JB, Lee SH, ''et al.'' |title=Imaging of Marfan syndrome: multisystemic manifestations |journal=Radiographics |volume=27 |issue=4 |pages=989–1004 |year=2007 |pmid=17620463 |doi=10.1148/rg.274065171 |url=http://radiographics.rsna.org/content/27/4/989.full}}</ref>
*Basophilic ground substance in the media (seen on Movat's [[stain]]).
*Disruption of the elastic lamina (seen on elastic trichrome stain).
*+/-Focal necrosis.
 
====Images====
<gallery>
Image:Cystic_medial_degeneration_-_low_mag.jpg | Cystic medial degeneration - low mag. (WC/Nephron)
Image:Cystic_medial_degeneration_-_high_mag.jpg | Cystic medial degeneration - high mag. (WC/Nephron)
Image:Cystic_medial_degeneration_-_movat_-_low_mag.jpg | Cystic medial degeneration - movat - low mag. (WC/Nephron)
Image:Cystic_medial_degeneration_-_movat_-_intermed_mag.jpg | Cystic medial degeneration - movat - intermed. mag. (WC/Nephron)
</gallery>
www:
*[http://radiographics.rsna.org/content/27/4/989.full Marfan's syndrome (radiographics.rsna.org)].
 
===Stains===
*Elastin stains (e.g. [[elastic trichrome stain]]) - disruption of the elastic lamina.
*[[Movat's stain]] - basophilic ground substance in the media.


==Medial calcific sclerosis==
==Medial calcific sclerosis==
*[[AKA]] ''Moenckeberg medial calcific sclerosis'', ''calcific medial sclerosis of Monckeberg'', and ''Monckeberg's arteriosclerosis''.
[[AKA]] ''Moenckeberg medial calcific sclerosis'', ''calcific medial sclerosis of Monckeberg'', and ''Monckeberg's arteriosclerosis''.
===General===
{{Main|Medial calcific sclerosis}}
*Usually of no clinical consequence.
 
===Microscopic===
Features:<ref name=Ref_Klatt7>{{Ref Klatt|7}}</ref>
*Medial calcification (purple irregular stuff on [[H&E stain|H&E]] -- calcium phosphate).
 
Note:
*Lumen unaffected.
 
====Images====
<gallery>
Image:Calcificatio_atherosclerotica.jpg | MCS. (WC)
</gallery>
www:
*[http://library.med.utah.edu/WebPath/COW/COW086.html Moenckeberg medial calcific sclerosis (med.utah.edu)].
 
===Sign out===
<pre>
RIGHT LEG, BELOW KNEE AMPUTATION:
- MINIMAL-TO-MILD LARGE VESSEL ATHEROSCLEROSIS, SEE COMMENT.
- MEDIAL CALCIFIC SCLEROSIS.
- SKIN WITH DERMAL FIBROSIS.
 
COMMENT:
The sections may not be representative of disease in the distal vascular bed.
</pre>


==Hyperplastic arteriolosclerosis==
==Hyperplastic arteriolosclerosis==
Michael
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