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Difference between revisions of "Vascular disease"
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+atherosclerosis
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(+atherosclerosis) |
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==Great vessels== | ==Great vessels== | ||
When things go wrong here, you see a cardiac surgeon. | When things go wrong here, you see a cardiac surgeon. | ||
==Atherosclerosis== | |||
===General=== | |||
*Cardiac atherosclerosis -> myocardial infarction, coronary thrombosis. | |||
*Peripheral atherosclerosis -> peripheral vascular disease -> amputations. | |||
*Carotid atherosclerosis -> thrombotic stroke. | |||
Clinical risk factors: | |||
*Age. | |||
*Blood pressure - modifiable (antihypertensives). | |||
*Cholesterol - modifiable (statins, diet). | |||
*Diabetes mellitus - modifiable (hypoglycemic medications, diet, lifestyle). | |||
*Smoking - modifiable (cessation). | |||
*Family history. | |||
===Microscopic=== | |||
Features: | |||
*Intimal hyperplasia. | |||
*Lipid deposition. | |||
*Foam macrophages within intima & media. | |||
*Cholesterol clefts | |||
*Luminal narrowing. | |||
==Aortic dissection== | ==Aortic dissection== | ||