Difference between revisions of "Urinary bladder amyloidosis"

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*Primary bladder amyloidosis is rare - approximately 200 reported cases as of 2014.<ref name=pmid25366012/><ref name=pmid24857645/>
*Primary bladder amyloidosis is rare - approximately 200 reported cases as of 2014.<ref name=pmid25366012/><ref name=pmid24857645/>
**Systemic [[amyloidosis]] should be excluded.<ref name=pmid24857645>{{Cite journal  | last1 = Schou-Jensen | first1 = KS. | last2 = Dahl | first2 = C. | last3 = Pilt | first3 = AP. | last4 = Azawi | first4 = NH. | title = Amyloidosis in the bladder: three cases with different appearance. | journal = Scand J Urol | volume = 48 | issue = 5 | pages = 489-92 | month = Oct | year = 2014 | doi = 10.3109/21681805.2014.920414 | PMID = 24857645 }}</ref>
**Systemic [[amyloidosis]] should be excluded.<ref name=pmid24857645>{{Cite journal  | last1 = Schou-Jensen | first1 = KS. | last2 = Dahl | first2 = C. | last3 = Pilt | first3 = AP. | last4 = Azawi | first4 = NH. | title = Amyloidosis in the bladder: three cases with different appearance. | journal = Scand J Urol | volume = 48 | issue = 5 | pages = 489-92 | month = Oct | year = 2014 | doi = 10.3109/21681805.2014.920414 | PMID = 24857645 }}</ref>
*May clinically mimic bladder cancer.<ref name=pmid25366012/>
*May clinically mimic [[bladder cancer]].<ref name=pmid25366012/>


==Gross==
==Gross==
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==Microscopic==
==Microscopic==
Features:
Features:
*Lamina propria with amyloid (amorphous, paucicellular, pink material on H&E - classically "cracked").
*Lamina propria with amyloid.
**Amyloid = amorphous, paucicellular material that is [[pink on H&E]], classically has "cracked" appearance.
***"Cracked": irregular fragments where the edges and centre of fragments are homogeneous.


DDx:
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