Urethral caruncle

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Urethral caruncle is a rare benign pathology of the urethra.

General

  • Definition as per Genitourinary Pathology by Zhou:[1] polypoid lesion of the distal urethra in women that ought to have lamina propria inflammation.
  • Benign.
  • Typically in post-menopausal women.
  • Reported in men.[2]

Clinical:[3]

  • +/-Dysuria.
  • +/-Hematuria.

Microscopic

Features:[4]

  • Polypoid or sessile lesion - covered with squamous epithelium or urothelium.
  • +/-Inflammation.
  • +/-Dilated blood vessels.

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Urethral Caruncle, Excision or Biopsy:
	- Consistent with urethral caruncle.
	- NEGATIVE for malignancy.

Micro

The specimen consists of a polypoid fragment of predominantly squamous mucosa with parakeratosis and glycogen-like change and mild inflammation. Urothelial mucosa with chronic active inflammation is present. The specimen is negative for significant atypia and negative for readily apparent proliferation.

See also

References

  1. Zhou, Ming; Magi-Galluzzi, Cristina (2006). Genitourinary Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 457. ISBN 978-0443066771.
  2. Sriprasad, S.; Kooiman, GG.; Hopster, D.; Muir, GH. (Dec 2003). "Urethral caruncle in a man.". BJU Int 92 Suppl 3: e68. PMID 19125457.
  3. URL: http://www.riversideonline.com/health_reference/Questions-Answers/AN01214.cfm. Accessed on: 3 February 2012.
  4. Kim, KK.; Sin, DY.; Park, HW. (Apr 1993). "Urethral caruncle occurring in a young girl--a case report.". J Korean Med Sci 8 (2): 160-1. PMID 8397932.