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Difference between revisions of "Urachal carcinoma"
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→Microscopic
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==Microscopic== | ==Microscopic== | ||
Features: | Features of epithelial malignancy: | ||
*Atypical cells. | *Atypical (epithelial) cells. | ||
**May be signet ring cells. | **May be [[signet ring cells]]. | ||
*Usually gland forming, i.e. adenocarcinoma. | *Usually gland forming, i.e. adenocarcinoma. | ||
*+/-Mucinous component. | *+/-Mucinous component. | ||
Features making it urothelial carcinoma (modified Sheldon criteria) - all required:<ref name=pmid22301493>{{Cite journal | last1 = Paner | first1 = GP. | last2 = Barkan | first2 = GA. | last3 = Mehta | first3 = V. | last4 = Sirintrapun | first4 = SJ. | last5 = Tsuzuki | first5 = T. | last6 = Sebo | first6 = TJ. | last7 = Jimenez | first7 = RE. | title = Urachal carcinomas of the nonglandular type: salient features and considerations in pathologic diagnosis. | journal = Am J Surg Pathol | volume = 36 | issue = 3 | pages = 432-42 | month = Mar | year = 2012 | doi = 10.1097/PAS.0b013e31823fe49c | PMID = 22301493 }}</ref> | |||
#Located in bladder dome or anterior wall. | |||
#Centered on bladder wall (as opposed to the mucosa). | |||
#No widespread cystitis cystica/glandularis outside of the bladder dome and anterior wall. | |||
#No known urothelial neoplasm elsewhere. | |||
DDx:<ref name=Ref_Amin2-143>{{Ref Amin|2-143}}</ref> | DDx:<ref name=Ref_Amin2-143>{{Ref Amin|2-143}}</ref> | ||
*[[Adenocarcinoma of the urinary bladder]]. | *[[Adenocarcinoma of the urinary bladder]]. | ||