Difference between revisions of "Tuberous sclerosis-associated renal cell carcinoma"

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==Microscopic==
==Microscopic==
Features as per Guo ''et al.''<ref name=pmid25093518/> describes three different morphologies:
Features as per Guo ''et al.''<ref name=pmid25093518/> describes three different morphologies:
*#[[Renal angiomyoadenomatous tumour]]-like.
#[[Renal angiomyoadenomatous tumour]]-like.
*#[[Chromophobe renal cell carcinoma]]-like.
#[[Chromophobe renal cell carcinoma]]-like.
*#Macrocystic architecture composed of cells with a granular eosinophilic cytoplasm.
#Macrocystic architecture composed of cells with a granular eosinophilic cytoplasm.


Notes:
Notes:

Revision as of 07:31, 11 December 2014

Tuberous sclerosis-associated renal cell carcinoma, abbreviated TSARCC, is a kidney tumour that is associated with the syndrome tuberous sclerosis.[1]

General

Microscopic

Features as per Guo et al.[1] describes three different morphologies:

  1. Renal angiomyoadenomatous tumour-like.
  2. Chromophobe renal cell carcinoma-like.
  3. Macrocystic architecture composed of cells with a granular eosinophilic cytoplasm.

Notes:

DDx:

See also

References

  1. 1.0 1.1 Guo, J.; Tretiakova, MS.; Troxell, ML.; Osunkoya, AO.; Fadare, O.; Sangoi, AR.; Shen, SS.; Lopez-Beltran, A. et al. (Nov 2014). "Tuberous Sclerosis-associated Renal Cell Carcinoma: A Clinicopathologic Study of 57 Separate Carcinomas in 18 Patients.". Am J Surg Pathol 38 (11): 1457-67. doi:10.1097/PAS.0000000000000248. PMID 25093518.
  2. Bjornsson, J.; Short, MP.; Kwiatkowski, DJ.; Henske, EP. (Oct 1996). "Tuberous sclerosis-associated renal cell carcinoma. Clinical, pathological, and genetic features.". Am J Pathol 149 (4): 1201-8. PMID 8863669.
  3. 3.0 3.1 Yang, P.; Cornejo, KM.; Sadow, PM.; Cheng, L.; Wang, M.; Xiao, Y.; Jiang, Z.; Oliva, E. et al. (Jul 2014). "Renal cell carcinoma in tuberous sclerosis complex.". Am J Surg Pathol 38 (7): 895-909. doi:10.1097/PAS.0000000000000237. PMID 24832166.