Difference between revisions of "Traditional serrated adenoma"

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| Rads      =
| Rads      =
| Endoscopy  =  
| Endoscopy  =  
| Prognosis  =
| Prognosis  = benign (pre-malignant)
| Other      =
| Other      =
| ClinDDx    = other [[GI polyps]]
| ClinDDx    = other [[GI polyps]]
| Tx        = polypectomy
}}
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'''Traditional serrated adenoma''', abbreviated '''TSA''', are a rare type of [[gastrointestinal polyp]].  
'''Traditional serrated adenoma''', abbreviated '''TSA''', are a rare type of [[gastrointestinal polyp]].  

Revision as of 05:50, 13 March 2015

Traditional serrated adenoma
Diagnosis in short

LM serrated, eosinophilic cytoplasm, villous-like architecture
LM DDx villous adenoma
Site colon - usu. left side / gastrointestinal polyps

Prevalence very rare
Prognosis benign (pre-malignant)
Clin. DDx other GI polyps
Treatment polypectomy

Traditional serrated adenoma, abbreviated TSA, are a rare type of gastrointestinal polyp.

Before the sessile serrated adenomas were recognized, these lesions were known as serrated adenomas.[1]

General

  • Very rare.
  • Pre-malignant.[2]

Gross

  • Polypoid mass.
  • Usually in the left colon.

Microscopic

Features:[3]

  • Serrated - essential.
  • Eosinophilic cytoplasm - key feature.
  • Nuclear atypia as in tubular adenoma.
    • Nuclear hyperchromasia, enlargement and pseudostratification.
  • Villous-like architecture.

DDx:

Images

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POLYP, SIGMOID COLON, POLYPECTOMY:
- TRADITIONAL SERRATED ADENOMA.
-- NEGATIVE FOR HIGH-GRADE DYSPLASIA.

See also

References

  1. Noffsinger, AE.; Hart, J. (Jul 2010). "Serrated adenoma: a distinct form of non-polypoid colorectal neoplasia?". Gastrointest Endosc Clin N Am 20 (3): 543-63. doi:10.1016/j.giec.2010.03.012. PMID 20656251.
  2. Rosty, C.; Hewett, DG.; Brown, IS.; Leggett, BA.; Whitehall, VL. (Mar 2013). "Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management.". J Gastroenterol 48 (3): 287-302. doi:10.1007/s00535-012-0720-y. PMID 23208018.
  3. Li SC, Burgart L (March 2007). "Histopathology of serrated adenoma, its variants, and differentiation from conventional adenomatous and hyperplastic polyps". Arch. Pathol. Lab. Med. 131 (3): 440-5. PMID 17516746. http://journals.allenpress.com/jrnlserv/?request=get-abstract&issn=0003-9985&volume=131&page=440.