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Difference between revisions of "Thyroid transcription factor-1"
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Thyroid transcription factor-1 (view source)
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===Positive staining=== | ===Positive staining=== | ||
*[[Lung adenocarcinoma]].<ref name=pmid12023581>{{Cite journal | last1 = Yatabe | first1 = Y. | last2 = Mitsudomi | first2 = T. | last3 = Takahashi | first3 = T. | title = TTF-1 expression in pulmonary adenocarcinomas. | journal = Am J Surg Pathol | volume = 26 | issue = 6 | pages = 767-73 | month = Jun | year = 2002 | doi = | PMID = 12023581 }}</ref> | *[[Lung adenocarcinoma]].<ref name=pmid12023581>{{Cite journal | last1 = Yatabe | first1 = Y. | last2 = Mitsudomi | first2 = T. | last3 = Takahashi | first3 = T. | title = TTF-1 expression in pulmonary adenocarcinomas. | journal = Am J Surg Pathol | volume = 26 | issue = 6 | pages = 767-73 | month = Jun | year = 2002 | doi = | PMID = 12023581 }}</ref> | ||
**[[Small cell carcinoma of the lung]]. | **[[Small cell carcinoma of the lung]] ~ 91% positive (157 +ve of 173<ref name=pmid37139017>{{cite journal |authors=Sayeda S, Naqvi A, Begum H, Juergens RA, Finley C, Coschi CH, Cutz JC, Bonert M |title=Prevalence of Thyroid Transcription Factor-1 (TTF-1)-Negative Small Cell Carcinoma and Napsin A Positivity in Small Cell Carcinoma in a Cross-Sectional Study of Lung Core Biopsies |journal=Cureus |volume=15 |issue=4 |pages=e37015 |date=April 2023 |pmid=37139017 |pmc=10151064 |doi=10.7759/cureus.37015 |url=}}</ref>). | ||
**[[Adenocarcinoma of the lung]]. | **[[Adenocarcinoma of the lung]]. | ||
*Thyroid carcinoma. | *Thyroid carcinoma. | ||
*[[Hepatocellular carcinoma]] (cytoplasmic staining).<ref name=pmid22359993>{{Cite journal | last1 = Mishra | first1 = M. | last2 = Morgan | first2 = V. | last3 = Hamati | first3 = AK. | last4 = Al-Abbadi | first4 = M. | title = Carcinoma of unknown primary: check the liver... thanks to TTF-1. | journal = Tenn Med | volume = 105 | issue = 1 | pages = 35-6, 40 | month = Jan | year = 2012 | doi = | PMID = 22359993 }}</ref> | *[[Hepatocellular carcinoma]] (cytoplasmic staining, nuclei negative).<ref name=pmid22359993>{{Cite journal | last1 = Mishra | first1 = M. | last2 = Morgan | first2 = V. | last3 = Hamati | first3 = AK. | last4 = Al-Abbadi | first4 = M. | title = Carcinoma of unknown primary: check the liver... thanks to TTF-1. | journal = Tenn Med | volume = 105 | issue = 1 | pages = 35-6, 40 | month = Jan | year = 2012 | doi = | PMID = 22359993 }}</ref> | ||
* Spindle cell oncocytoma / Pituicytoma / Granular cell tumor of the pituitary. <ref name=pmid23887161> {{Cite journal | last1 = Mete | first1 = O. | last2 = Lopes | first2 = MB. | last3 = Asa | first3 = SL. | title = Spindle cell oncocytomas and granular cell tumors of the pituitary are variants of pituicytoma. | journal = Am J Surg Pathol | volume = 37 | issue = 11 | pages = 1694-9 | month = Nov | year = 2013 | doi = 10.1097/PAS.0b013e31829723e7 | PMID = 23887161 }}</ref> | * Spindle cell oncocytoma / Pituicytoma / Granular cell tumor of the pituitary. <ref name=pmid23887161> {{Cite journal | last1 = Mete | first1 = O. | last2 = Lopes | first2 = MB. | last3 = Asa | first3 = SL. | title = Spindle cell oncocytomas and granular cell tumors of the pituitary are variants of pituicytoma. | journal = Am J Surg Pathol | volume = 37 | issue = 11 | pages = 1694-9 | month = Nov | year = 2013 | doi = 10.1097/PAS.0b013e31829723e7 | PMID = 23887161 }}</ref> | ||
*[[Subependymal giant cell astrocytoma]] <ref name=pmid25669749>{{Cite journal | last1 = Hewer | first1 = E. | last2 = Vajtai | first2 = I. | title = Consistent nuclear expression of thyroid transcription factor 1 in subependymal giant cell astrocytomas suggests lineage-restricted histogenesis. | journal = Clin Neuropathol | volume = 34 | issue = 3 | pages = 128-31 | month = | year = | doi = 10.5414/NP300818 | PMID = 25669749 }}</ref> | *[[Subependymal giant cell astrocytoma]] <ref name=pmid25669749>{{Cite journal | last1 = Hewer | first1 = E. | last2 = Vajtai | first2 = I. | title = Consistent nuclear expression of thyroid transcription factor 1 in subependymal giant cell astrocytomas suggests lineage-restricted histogenesis. | journal = Clin Neuropathol | volume = 34 | issue = 3 | pages = 128-31 | month = | year = | doi = 10.5414/NP300818 | PMID = 25669749 }}</ref> | ||