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Difference between revisions of "Testis"
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→Seminoma: more images
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*Rarely, it may present a retroperitoneal mass.<ref name=pmid21424055>{{Cite journal | last1 = Preda | first1 = O. | last2 = Nicolae | first2 = A. | last3 = Loghin | first3 = A. | last4 = Borda | first4 = A. | last5 = Nogales | first5 = FF. | title = Retroperitoneal seminoma as a first manifestation of a partially regressed (burnt-out) testicular germ cell tumor. | journal = Rom J Morphol Embryol | volume = 52 | issue = 1 | pages = 193-6 | month = | year = 2011 | doi = | PMID = 21424055 }}</ref> | *Rarely, it may present a retroperitoneal mass.<ref name=pmid21424055>{{Cite journal | last1 = Preda | first1 = O. | last2 = Nicolae | first2 = A. | last3 = Loghin | first3 = A. | last4 = Borda | first4 = A. | last5 = Nogales | first5 = FF. | title = Retroperitoneal seminoma as a first manifestation of a partially regressed (burnt-out) testicular germ cell tumor. | journal = Rom J Morphol Embryol | volume = 52 | issue = 1 | pages = 193-6 | month = | year = 2011 | doi = | PMID = 21424055 }}</ref> | ||
===Epidemiology & etiology=== | ====Epidemiology & etiology==== | ||
*Arises from ''intratubular germ cell neoplasia'' (ITGCN). | *Arises from ''[[intratubular germ cell neoplasia]]'' (ITGCN). | ||
===Microsopic=== | ===Microsopic=== | ||
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Memory device: 3 Cs - clear cytoplasm, central nucleus, corners on the nuclear membrane. | Memory device: 3 Cs - clear cytoplasm, central nucleus, corners on the nuclear membrane. | ||
DDx: | DDx: | ||
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*[[Choriocarcinoma]] - esp. if (multinucleated) syncytiotrophoblasts are present.<ref name=pmid157614>{{Cite journal | last1 = Hedinger | first1 = C. | last2 = von Hochstetter | first2 = AR. | last3 = Egloff | first3 = B. | title = Seminoma with syncytiotrophoblastic giant cells. A special form of seminoma. | journal = Virchows Arch A Pathol Anat Histol | volume = 383 | issue = 1 | pages = 59-67 | month = Jul | year = 1979 | doi = | PMID = 157614 }}</ref> | *[[Choriocarcinoma]] - esp. if (multinucleated) syncytiotrophoblasts are present.<ref name=pmid157614>{{Cite journal | last1 = Hedinger | first1 = C. | last2 = von Hochstetter | first2 = AR. | last3 = Egloff | first3 = B. | title = Seminoma with syncytiotrophoblastic giant cells. A special form of seminoma. | journal = Virchows Arch A Pathol Anat Histol | volume = 383 | issue = 1 | pages = 59-67 | month = Jul | year = 1979 | doi = | PMID = 157614 }}</ref> | ||
*Granulomatous orchitis - if [[granuloma]]s are present. | *Granulomatous orchitis - if [[granuloma]]s are present. | ||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Seminoma_high_mag.jpg Seminoma - high mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Seminoma_intermed_mag.jpg Seminoma - intermed. mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Seminoma_with_syncytiotrophoblasts_-_intermed_mag.jpg Seminoma with syncytiotrophoblasts - intermed. mag. (WC)]. | |||
*[http://commons.wikimedia.org/wiki/File:Seminoma_with_syncytiotrophoblasts_-_very_high_mag.jpg Seminoma with syncytiotrophoblasts - very high mag. (WC)]. | |||
===IHC=== | ===IHC=== | ||