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Difference between revisions of "Testis"
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→Microsopic: tweak
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===Microsopic=== | ===Microsopic=== | ||
Features: | Features: | ||
*Cells with fried egg appearance | *Cells with fried egg appearance - '''key feature''': | ||
**Clear cytoplasm. | **Clear cytoplasm. | ||
**Central nucleus, with prominent nucleolus. | **Central nucleus, with prominent nucleolus. | ||
***Nucleus | ***Nucleus may have "corners", i.e. it is ''not'' round. | ||
*Lymphoctyes common | *+/-Lymphoctyes - interspersed (very common). | ||
* | *+/-[[Syncytiotrophoblast]]s, [[AKA]] ''syncytiotrophoblastic giant cells'' (STGCs),<ref name=Ref_GUP542>{{Ref GUP|542}}</ref> present in ~10-20% of seminoma.<ref>URL: [http://www.webpathology.com/image.asp?case=31&n=10 http://www.webpathology.com/image.asp?case=31&n=10]. Accessed on: 22 May 2012.</ref> | ||
**Large + irregular, vesicular nuclei. | **Large + irregular, vesicular nuclei. | ||
**Eosinophilic vacuolated cytoplasm (contains hCG). | **Eosinophilic vacuolated cytoplasm (contains hCG). | ||
***Syncytiotrophoblasts = closest to mom in normal [[chorionic villi]] - covers cytotrophoblast.<ref>URL: [http://upload.wikimedia.org/wikipedia/commons/4/45/Gray37.png http://upload.wikimedia.org/wikipedia/commons/4/45/Gray37.png]. Accessed on: 31 May 2010.</ref> | ***Syncytiotrophoblasts = closest to mom in normal [[chorionic villi]] - covers cytotrophoblast.<ref>URL: [http://upload.wikimedia.org/wikipedia/commons/4/45/Gray37.png http://upload.wikimedia.org/wikipedia/commons/4/45/Gray37.png]. Accessed on: 31 May 2010.</ref> | ||
* | *+/-Florid granulomatous reaction. | ||
Memory device: 3 Cs - clear cytoplasm, central nucleus, corners on the nuclear membrane. | Memory device: 3 Cs - clear cytoplasm, central nucleus, corners on the nuclear membrane. | ||