Talk:Thyroid gland

Neck dissection

Microscopic description

A, B, C. The sections show lymph nodes invaded by a papillae-forming neoplasm with scattered, easy-to-find pseudonuclear inclusions, prominent nucleoli, focal nuclear membrane overlap, nuclear clearing, mild-to-moderate nuclear size variation, nuclear grooves and rare psammomatous calcifications. Mitotic activity is not identified.

Part A only: Thymus is present with focal degeneration of the thymic corpulses, tingible-body macrophages, and focal lymphocyte drop-out. There is benign parathyroid tissue with scant adipose tissue. There is a cluster of tumour cells (as described above) that is not adjacent to encapulated lymphoid tissue.

Final diagnosis

A. Central neck mass, excision
- Four of five lymph nodes positive for papillary thyroid carcinoma ( 4 / 5 ), see comment 1.
- Benign parathyroid gland.
- Thymus with mild-to-moderate stress reaction.

B. Neck mass, level 3-4, excision - Four of eleven lymph nodes positive for papillary thryoid carcinoma ( 4 / 11).

C. Neck mass, zone 2, excision - One of six lymph nodes positive for papillary thyroid carcinoma.

See diagnosis comment 2.

Comment

Comment 1: There is a cluster of tumour cells without adjacent lymphoid tissue. This is thought to represent extranodal extension; however, it may represent a tumour deposit.
Comment 2: The lymph node counts in part A, B and C are estimates, as the lymph nodes were matted.