Difference between revisions of "Talk:Prostate gland"

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==Prostate biopsy - 4 cores==
===Final===
1. Prostate, right lateral, biopsy:
- Negative for malignancy.
2. Prostate, right medial, biopsy:
- Negative for malignancy.
3. Prostate, left medial, biopsy:
- Negative for malignancy.
4. Prostate, left lateral, biopsy:
- Negative for malignancy.
==Prostate biopsy - 5 cores==
==Prostate biopsy - 5 cores==
===Final===
===Final===
Line 19: Line 33:
- Negative for malignancy.
- Negative for malignancy.


==Prostate biopsy - 6 cores==
==Prostate biopsy - 6 cores (apex, mid, base)==
===Final===
===Final===
1. Prostate, right apex peripheral, biopsy:
1. Prostate, right apex peripheral, biopsy:
Line 38: Line 52:
6. Prostate, left base, biopsy:
6. Prostate, left base, biopsy:
- Benign prostatic tissue.
- Benign prostatic tissue.
==Prostate biopsy - 6 cores (base, mid, apex)==
===Final===
1. Prostate, right base, biopsy:
- Negative for malignancy.
2. Prostate, right mid, biopsy:
- Adenocarcinoma, Gleason score 7/10 (3+4);
- 2/2 cores involved - 1st core: 80% of tissue, 2nd core: 55% of tissue;
- approximately 70% of all tissue involved.
3. Prostate, right apex, biopsy:
- Negative for malignancy.
4. Prostate, left base, biopsy:
- Atypical small acinar proliferation.
5. Prostate, left mid, biopsy:
- Negative for malignancy.
- Acute and chronic inflammation.
6. Prostate, left apex, biopsy:
- Negative for malignancy.


==Prostate biopsy - 7 cores==
==Prostate biopsy - 7 cores==
Line 140: Line 178:
12. Prostate, left apex medial, biopsy:
12. Prostate, left apex medial, biopsy:
- Benign prostate tissue.
- Benign prostate tissue.
==Prostate biopsy - 12 cores - alternate==
===Final===
<pre>
1. PROSTATE, RIGHT LATERAL SUPERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.
2. PROSTATE, RIGHT MEDIAL SUPERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.
3. PROSTATE, RIGHT LATERAL MIDZONE, BIOPSY:
- BENIGN PROSTATE TISSUE.
4. PROSTATE, RIGHT MEDIAL MIDZONE, BIOPSY:
- BENIGN FIBROMUSCULAR TISSUE;
- NO PROSTATIC GLANDULAR TISSUE PRESENT.
5. PROSTATE, RIGHT LATERAL INTERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.
6. PROSTATE, RIGHT MEDIAL INFERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.
7. PROSTATE, LEFT LATERAL SUPERIOR, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4);
- 1/1 CORE INVOLVED; APPROXIMATELY 15% OF TISSUE INVOLVED.
8. PROSTATE, LEFT MEDIAL SUPERIOR, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 7/10 (4+3);
- 1/1 CORE INVOLVED; APPROXIMATELY 5% OF TISSUE INVOLVED;
- FOCAL PERINEURAL INVASION PRESENT.
9. PROSTATE, LEFT LATERAL MIDZONE, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4);
- 1/1 CORE INVOLVED; APPROXIMATELY 50% OF TISSUE INVOLVED.
10. PROSTATE, LEFT MEDIAL MIDZONE, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4);
- 1/1 CORE INVOLVED; APPROXIMATELY 20% OF TISSUE INVOLVED.
11. PROSTATE, LEFT LATERAL INTERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.
12. PROSTATE, LEFT MEDIAL INFERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.
</pre>
== Soft tissue granulomas ==
<pre>
J. PROSTATE, LEFT MEDIAL MIDZONE, BIOPSY:
- BENIGN PROSTATE TISSUE;
- FOREIGN BODY-TYPE GRANULOMA, NONNECROTIZING, SEE COMMENT.
COMMENT:
The granulomas appear to be within the periprostatic soft tissue. They consist of
multinucleated (foreign body-type) giant cells, hyaline material and rare interspersed
neutrophils. No necrosis is identified. This finding may represent a reaction to displaced
epithelium from a previous procedure.
</pre>
== Weight ==
http://www.ncbi.nlm.nih.gov/pubmed/24053335
groups: <30, 30-50, >50
http://www.ncbi.nlm.nih.gov/pubmed/23795788
volume >80 mL
==Inflammation==
===Micro===
The sections show prostate cores with marked inflammation, that partially obscures the gland
outlines. The inflammation is predominantly lymphocytic with a lesser amount of
neutrophils and plasma cells.  Eosinophils are not readily apparent.  An isolated granuloma
without necrosis is seen in one core.
The gland-to-stroma ratio is within normal limits. Basal cells are identified in
the glands. Reactive nuclear changes are present. The gland architecture does not show
changes characteristic of neoplasia.

Latest revision as of 16:42, 30 November 2013

Prostate biopsy - 4 cores

Final

1. Prostate, right lateral, biopsy: - Negative for malignancy.

2. Prostate, right medial, biopsy: - Negative for malignancy.

3. Prostate, left medial, biopsy: - Negative for malignancy.

4. Prostate, left lateral, biopsy: - Negative for malignancy.

Prostate biopsy - 5 cores

Final

1. Prostate, right lateral, biopsy: - Adenocarcinoma, Gleason score 7/10 (3+4); - 1/1 core involved; approximately 5% of tissue involved.

2. Prostate, right medial, biopsy: - Adenocarcinoma, Gleason score 7/10 (3+4); - 1/1 core involved; approximately 40% of tissue involved.

3. Prostate nodule, left transition zone, biopsy: - Adenocarcinoma, Gleason score 7/10 (3+4); - 1/1 core involved; approximately 40% of tissue involved.

4. Prostate, left medial, biopsy: - Negative for malignancy.

5. Prostate, left lateral, biopsy: - Negative for malignancy.

Prostate biopsy - 6 cores (apex, mid, base)

Final

1. Prostate, right apex peripheral, biopsy: - Benign prostate tissue.

2. Prostate, right mid, biopsy: - Benign prostatic tissue.

3. Prostate, right base, biopsy: - Benign prostatic tissue.

4. Prostate, left apex, biopsy: - Benign prostatic tissue.

5. Prostate, left mid, biopsy: - Benign prostatic tissue.

6. Prostate, left base, biopsy: - Benign prostatic tissue.


Prostate biopsy - 6 cores (base, mid, apex)

Final

1. Prostate, right base, biopsy: - Negative for malignancy.

2. Prostate, right mid, biopsy: - Adenocarcinoma, Gleason score 7/10 (3+4); - 2/2 cores involved - 1st core: 80% of tissue, 2nd core: 55% of tissue; - approximately 70% of all tissue involved.

3. Prostate, right apex, biopsy: - Negative for malignancy.

4. Prostate, left base, biopsy: - Atypical small acinar proliferation.

5. Prostate, left mid, biopsy: - Negative for malignancy. - Acute and chronic inflammation.

6. Prostate, left apex, biopsy: - Negative for malignancy.

Prostate biopsy - 7 cores

Final

1. Prostate, right lateral, biopsy: - Negative for malignancy.

2. Prostate, right medial, biopsy: - Negative for malignancy. - Focal chronic inflammation.

3. Prostate, right transition zone, biopsy: - Negative for malignancy.

4. Prostate, mid, biopsy: - Negative for malignancy.

5. Prostate, left transition zone, biopsy: - Negative for malignancy. - Focal chronic inflammation.

6. Prostate, left medial, biopsy: - Negative for malignancy.

7. Prostate, left lateral, biopsy: - Atypical small acinar proliferation.

Prostate biopsy - 10 cores

Final

1. Prostate, right base peripheral, biopsy: - Benign prostate tissue.

2. Prostate, right mid peripheral, biopsy: - Benign prostate tissue.

3. Prostate, right apex peripheral, biopsy: - Benign prostate tissue.

4. Prostate, right base central, biopsy: - Benign prostate tissue.

5. Prostate, right mid central, biopsy: - Adenocarcinoma, Gleason score 6/10 (3+3); - 1/1 core involved; approximately 5% of tissue involved.

6. Prostate, left base peripheral, biopsy: - Atypical small acinar proliferation.

7. Prostate, left mid peripheral, biopsy: - Benign prostatic tissue.

8. Prostate, left apex peripheral, biopsy: - Benign prostatic tissue.

9. Prostate, left base central, biopsy: - Benign prostatic tissue.

10. Prostate, left mid central, biopsy: - Benign prostatic tissue.

Prostate biopsy - 12 cores

Final

1. Prostate, right base lateral, biopsy: - Benign prostate tissue.

2. Prostate, right base medial, biopsy: - Benign prostate tissue.

3. Prostate, right mid lateral, biopsy: - Benign prostate tissue.

4. Prostate, right mid medial, biopsy: - Benign fibromuscular tissue; - No prostatic glandular tissue present.

5. Prostate, right apex lateral, biopsy: - Benign prostate tissue.

6. Prostate, right apex medial, biopsy: - Benign prostate tissue.

7. Prostate, left base lateral, biopsy: - Adenocarcinoma, Gleason score 8/10 (4+4); - 1/1 core involved; approximately 15% of tissue involved.

8. Prostate, left base medial, biopsy: - Adenocarcinoma, Gleason score 7/10 (4+3); - 1/1 core involved; approximately 5% of tissue involved; - Focal perineural invasion present.

9. Prostate, right mid lateral, biopsy: - Adenocarcinoma, Gleason score 8/10 (4+4); - 1/1 core involved; approximately 50% of tissue involved.

10. Prostate, left mid medial, biopsy: - Adenocarcinoma, Gleason score 8/10 (4+4); - 1/1 core involved; approximately 20% of tissue involved.

11. Prostate, left apex lateral, biopsy: - Benign prostate tissue.

12. Prostate, left apex medial, biopsy: - Benign prostate tissue.

Prostate biopsy - 12 cores - alternate

Final

1. PROSTATE, RIGHT LATERAL SUPERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

2. PROSTATE, RIGHT MEDIAL SUPERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

3. PROSTATE, RIGHT LATERAL MIDZONE, BIOPSY:
- BENIGN PROSTATE TISSUE.

4. PROSTATE, RIGHT MEDIAL MIDZONE, BIOPSY:
- BENIGN FIBROMUSCULAR TISSUE;
- NO PROSTATIC GLANDULAR TISSUE PRESENT.

5. PROSTATE, RIGHT LATERAL INTERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

6. PROSTATE, RIGHT MEDIAL INFERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

7. PROSTATE, LEFT LATERAL SUPERIOR, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4);
- 1/1 CORE INVOLVED; APPROXIMATELY 15% OF TISSUE INVOLVED.

8. PROSTATE, LEFT MEDIAL SUPERIOR, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 7/10 (4+3);
- 1/1 CORE INVOLVED; APPROXIMATELY 5% OF TISSUE INVOLVED;
- FOCAL PERINEURAL INVASION PRESENT.

9. PROSTATE, LEFT LATERAL MIDZONE, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4);
- 1/1 CORE INVOLVED; APPROXIMATELY 50% OF TISSUE INVOLVED.

10. PROSTATE, LEFT MEDIAL MIDZONE, BIOPSY:
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4);
- 1/1 CORE INVOLVED; APPROXIMATELY 20% OF TISSUE INVOLVED.

11. PROSTATE, LEFT LATERAL INTERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

12. PROSTATE, LEFT MEDIAL INFERIOR, BIOPSY:
- BENIGN PROSTATE TISSUE.

Soft tissue granulomas

J. PROSTATE, LEFT MEDIAL MIDZONE, BIOPSY:
- BENIGN PROSTATE TISSUE;
- FOREIGN BODY-TYPE GRANULOMA, NONNECROTIZING, SEE COMMENT.

COMMENT:
The granulomas appear to be within the periprostatic soft tissue. They consist of
multinucleated (foreign body-type) giant cells, hyaline material and rare interspersed
neutrophils. No necrosis is identified. This finding may represent a reaction to displaced
epithelium from a previous procedure.

Weight

http://www.ncbi.nlm.nih.gov/pubmed/24053335 groups: <30, 30-50, >50


http://www.ncbi.nlm.nih.gov/pubmed/23795788 volume >80 mL

Inflammation

Micro

The sections show prostate cores with marked inflammation, that partially obscures the gland outlines. The inflammation is predominantly lymphocytic with a lesser amount of neutrophils and plasma cells. Eosinophils are not readily apparent. An isolated granuloma without necrosis is seen in one core.

The gland-to-stroma ratio is within normal limits. Basal cells are identified in the glands. Reactive nuclear changes are present. The gland architecture does not show changes characteristic of neoplasia.