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Difference between revisions of "Talk:Inflammatory bowel disease"
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Talk:Inflammatory bowel disease (view source)
Revision as of 16:25, 25 October 2013
, 16:25, 25 October 2013→Architectural changes: new section
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COMMENT: | COMMENT: | ||
The area of dysplasia may represent an IBD-related area | The area of dysplasia may represent an IBD-related area of polypoid dysplasia | ||
of polypoid dysplasia or a sporadic adenoma. This distinction | or a sporadic adenoma. This distinction cannot be made on morphology alone; | ||
cannot be made on morphology alone; clinical/endoscopic | clinical/endoscopic correlation is required. | ||
correlation is required. | |||
</pre> | </pre> | ||
== Re-anastomosis with mechanical reactive changes == | |||
<pre> | |||
"SMALL BOWEL", RESECTION AND NEW ANASTOMOSIS: | |||
- SMALL BOWEL WITH FOCAL MUCOSA EROSIONS -- FAVOUR MECHANICAL, SEE COMMENT. | |||
- LARGE BOWEL WITH POST-SURGICAL CHANGES, NEGATIVE FOR ACTIVE INFLAMMATION. | |||
- SKIN WITH REACTIVE CHANGES. | |||
- NEGATIVE FOR DYSPLASIA. | |||
COMMENT: | |||
The small bowel section focally shows erosions at the tips of the villi close to the | |||
interface with the skin; this is favoured to be a mechanical phenomenon. The small bowel | |||
more distant from the small bowel-skin junction shows no active inflammation. | |||
One foreign body-type granuloma is present. No other granulomata are identified. | |||
The bowel shows increased eosinophils and intraepithelial lymphocytes, and basal | |||
plasmacytosis compatible with a chronic inflammatory process. | |||
</pre> | |||
== Architectural changes == | |||
http://www.histopath.com.au/assets/documents/Inflammatory%20bowel%20disease.pdf | |||
Changes: | |||
*Gland branching. | |||
*Gland shortening. | |||
*Decreased gland density. | |||
*Variation of gland diameter. | |||