Difference between revisions of "Talk:Bone"

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m (giant cells)
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===Final diagnosis===
===Final diagnosis===
Humerous, right proximal, excision - Aneurysmal bone cyst.
Humerous, right proximal, excision - Aneurysmal bone cyst.
== Burnt-out chronic osteomyelitis ==
<pre>
GREAT TOE, LEFT, AMPUTATION:
- SKIN WITH ULCERATION AND IMPETIGINIZATION.
- ATHEROSCLEROSIS, MODERATE-TO-SEVERE.
- SOFT TISSUE WITH FIBROSIS AND CHRONIC INFLAMMATION.
- BONE AND MILDLY FIBROTIC MARROW SPACE WITH SCATTERED LYMPHOCYTES AND SIDEROPHAGES;
  NO SIGNIFICANT NUMBERS OF PLASMA CELLS OR NEUTROPHILS APPARENT.
- NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.
</pre>

Revision as of 19:54, 5 December 2013

Aneurysmal bone cyst

Microscopic description

The sections show cartilage, bone and osteoid with variable mineralization surrounded by fibroblasts, hemosiderin-laden macrophages, and multi-nucleated giant-cells with randomly arranged, round nuclei. Hemosiderin-laden macrophages are seen focally. There is no nuclear atypia or mitotic activity. There is no malignant appearing osteoid.

Final diagnosis

Humerous, right proximal, excision - Aneurysmal bone cyst.

Burnt-out chronic osteomyelitis

GREAT TOE, LEFT, AMPUTATION:
- SKIN WITH ULCERATION AND IMPETIGINIZATION.
- ATHEROSCLEROSIS, MODERATE-TO-SEVERE.
- SOFT TISSUE WITH FIBROSIS AND CHRONIC INFLAMMATION.
- BONE AND MILDLY FIBROTIC MARROW SPACE WITH SCATTERED LYMPHOCYTES AND SIDEROPHAGES;
  NO SIGNIFICANT NUMBERS OF PLASMA CELLS OR NEUTROPHILS APPARENT.
- NEGATIVE FOR DYSPLASIA AND NEGATIVE FOR MALIGNANCY.