48,452
edits
Difference between revisions of "TRK fusions"
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*Merestinib. | *Merestinib. | ||
*Larotrectinib.<ref name=pmid29466156>{{Cite journal | last1 = Drilon | first1 = A. | last2 = Laetsch | first2 = TW. | last3 = Kummar | first3 = S. | last4 = DuBois | first4 = SG. | last5 = Lassen | first5 = UN. | last6 = Demetri | first6 = GD. | last7 = Nathenson | first7 = M. | last8 = Doebele | first8 = RC. | last9 = Farago | first9 = AF. | title = Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children. | journal = N Engl J Med | volume = 378 | issue = 8 | pages = 731-739 | month = 02 | year = 2018 | doi = 10.1056/NEJMoa1714448 | PMID = 29466156 }}</ref> | *Larotrectinib.<ref name=pmid29466156>{{Cite journal | last1 = Drilon | first1 = A. | last2 = Laetsch | first2 = TW. | last3 = Kummar | first3 = S. | last4 = DuBois | first4 = SG. | last5 = Lassen | first5 = UN. | last6 = Demetri | first6 = GD. | last7 = Nathenson | first7 = M. | last8 = Doebele | first8 = RC. | last9 = Farago | first9 = AF. | title = Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children. | journal = N Engl J Med | volume = 378 | issue = 8 | pages = 731-739 | month = 02 | year = 2018 | doi = 10.1056/NEJMoa1714448 | PMID = 29466156 }}</ref> | ||
*Entrectinib.<ref name=pmid26565381>{{Cite journal | last1 = Farago | first1 = AF. | last2 = Le | first2 = LP. | last3 = Zheng | first3 = Z. | last4 = Muzikansky | first4 = A. | last5 = Drilon | first5 = A. | last6 = Patel | first6 = M. | last7 = Bauer | first7 = TM. | last8 = Liu | first8 = SV. | last9 = Ou | first9 = SH. | title = Durable Clinical Response to Entrectinib in NTRK1-Rearranged Non-Small Cell Lung Cancer. | journal = J Thorac Oncol | volume = 10 | issue = 12 | pages = 1670-4 | month = Dec | year = 2015 | doi = 10.1097/01.JTO.0000473485.38553.f0 | PMID = 26565381 }}</ref> | |||
*Others. | *Others. | ||