Difference between revisions of "TFE3-rearranged renal cell carcinoma"

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| Caption    = Xp11.2 translocation carcinoma. [[H&E stain]].  
| Caption    = Xp11.2 translocation carcinoma. [[H&E stain]].  
| Synonyms  = Xp11 translocation renal cell carcinoma, renal tumour with Xp11 translocation
| Synonyms  = Xp11 translocation renal cell carcinoma, renal tumour with Xp11 translocation, [[MiT family translocation renal cell carcinoma]] (obsolete term)
| Micro      = large cells with clear or eosinophilic cytoplasm, calcification (classic histomorphologic feature),  +/-papillae, +/-nests, +/-[[psammoma bodies]] (common), +/-[[hyaline bodies]] (common)
| Micro      = large cells with clear or eosinophilic cytoplasm, calcification (classic histomorphologic feature),  +/-papillae, +/-nests, +/-[[psammoma bodies]] (common), +/-[[hyaline bodies]] (common)
| Subtypes  =
| Subtypes  =
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| ClinDDx    = other [[kidney tumours]]
| ClinDDx    = other [[kidney tumours]]
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'''Renal tumour with Xp11.2 translocation''', also '''Xp11.2 translocation carcinoma''' and '''Xp11 translocation renal cell carcinoma''', is an uncommon [[malignant]] [[kidney tumour]] in the [[MiT family translocation renal cell carcinoma]].  
'''TFE3-rearranged renal cell carcinoma''' is a rare type of [[renal cell carcinoma]] recognized by the WHO classification as a distinct entity.<ref name=pmid36645398>{{cite journal |authors=Alaghehbandan R, Siadat F, Trpkov K |title=What's new in the WHO 2022 classification of kidney tumours? |journal=Pathologica |volume=115 |issue=1 |pages=8–22 |date=February 2022 |pmid=36645398 |pmc=10342217 |doi=10.32074/1591-951X-818 |url=}}</ref>


It should '''not''' be confused with ''[[renal tumour with t(6;11) translocation]]'' (also known as ''TFEB RCC''), another [[translocation carcinoma]] found in the [[kidney]] that is also in the ''MiT family translocation renal cell carcinoma''.  
It was previously known as '''renal tumour with Xp11.2 translocation''', also '''Xp11.2 translocation carcinoma''' and '''Xp11 translocation renal cell carcinoma'''. It was previously lumped with other entities in the category [[MiT family translocation renal cell carcinoma]].
 
It should '''not''' be confused with ''[[TFEB-rearranged RCC]]'', another [[translocation carcinoma]] found in the [[kidney]].


==General==
==General==
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