TDP-43

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TAR-DNA-binding Protein 43, abbreviated TDP-43 is a neuropathology immunostain used in neurodegenerative diseases.

  • Nuclear staining.
TDP-43
Immunostain in short

TDP-43 staining in FTLD-TDP43. (WC)
Normal staining pattern nuclear staining (physiological)
Positive cytoplasmatic staining (pathological)

Inclusion morphology

  • fine / coarse skeins.
  • dot-like.
  • dense-round inclusions.

Inclusions found


Images

See also

References

  1. Wilson, AC.; Dugger, BN.; Dickson, DW.; Wang, DS. (Jan 2011). "TDP-43 in aging and Alzheimer's disease - a review.". Int J Clin Exp Pathol 4 (2): 147-55. PMID 21326809.