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Difference between revisions of "Stomach"
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→Microscopic
(→IHC) |
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*''Helicobacter pylori'': | *''Helicobacter pylori'': | ||
**Typically have a "v" shape ''or'' a comma-like shape. | **Typically have a "v" shape ''or'' a comma-like shape. | ||
*''Helicobacter heilmannii'': | *''Helicobacter heilmannii'':<ref name=pmid16224223 >{{Cite journal | last1 = Singhal | first1 = AV. | last2 = Sepulveda | first2 = AR. | title = Helicobacter heilmannii gastritis: a case study with review of literature. | journal = Am J Surg Pathol | volume = 29 | issue = 11 | pages = 1537-9 | month = Nov | year = 2005 | doi = | PMID = 16224223 }}</ref> | ||
**Corkscrew appearance. | **Corkscrew appearance. | ||
Tips: | |||
*One needs to look at 400x magnification. Even at 400x they are possible to miss. | |||
**Helicobacter are damn small. They are smaller than the nucleus of the gastric foveollar cell. | |||
*Look for mucus - they preferentially reside there. | |||
**This is usually close to the opening of the gastric pits. | |||
*Helicobacter are found in groups. When you see several that are the same size and shape you can be sure they are real. | |||
Notes: | |||
*Helicobacter can be in antrum and/or body.<ref>{{cite journal |author=Maaroos HI, Kekki M, Villako K, Sipponen P, Tamm A, Sadeniemi L |title=The occurrence and extent of Helicobacter pylori colonization and antral and body gastritis profiles in an Estonian population sample |journal=Scand. J. Gastroenterol. |volume=25 |issue=10 |pages=1010-7 |year=1990 |month=October |pmid=2263873 |doi= |url=}}</ref> | |||
*Helicobacter don't like the intestinal mucosa ''or'' mucosa that has undergone [[intestinal metaplasia]]; you're unlikely to find 'em there. | |||
DDx: | |||
*Dirt - variable size. | |||
Images: | Images: | ||