Difference between revisions of "Squamous cell carcinoma of the head and neck"
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====Lymphoepithelial (squamous cell) carcinoma==== | ====Lymphoepithelial (squamous cell) carcinoma==== | ||
See ''[[nasopharyngeal carcinoma]]''. | See ''[[nasopharyngeal carcinoma]]''. | ||
==IHC== | |||
*p63 +ve. | |||
*EBER -ve. | |||
**Positive suggests [[nasopharyngeal carcinoma]]. | |||
*p16 -ve. | |||
**Positive suggests [[HPV-associated head and neck squamous cell carcinoma]]. | |||
*Bcl2 +ve/-ve. | |||
**Positive = poor prognosis.<ref name=pmid20233885>{{cite journal |author=Nichols AC, Finkelstein DM, Faquin WC, ''et al.'' |title=Bcl2 and human papilloma virus 16 as predictors of outcome following concurrent chemoradiation for advanced oropharyngeal cancer |journal=Clin. Cancer Res. |volume=16 |issue=7 |pages=2138–46 |year=2010 |month=April |pmid=20233885 |doi=10.1158/1078-0432.CCR-09-3185 |url=}}</ref> | |||
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