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Difference between revisions of "Squamous cell carcinoma"
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→Subtypes: update types, ref
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=Subtypes= | =Subtypes= | ||
There are several subtypes:<ref>URL: [http://www. | There are several subtypes:<ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/LipOralCav_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/LipOralCav_11protocol.pdf]. Accessed on: 3 April 2012.</ref> | ||
*Basaloid - poor prognosis, usu. diagnosed by recognition of typical SCC. | *Adenosquamous carcinoma. | ||
* | *Ancatholytic squamous cell carcinoma. | ||
*Verrucous - good prognosis, rare. | *Basaloid squamous cell carcinoma - poor prognosis, usu. diagnosed by recognition of typical SCC. | ||
*Papillary. | *Carcinoma cuniculatum. | ||
*Lymphoepithelial | *Verrucous carcinoma - good prognosis, rare. | ||
*Spindle cell | *Papillary squamous cell carcinoma. | ||
*Lymphoepithelial carcinoma - rare. | |||
*Spindle cell squamous carcinoma - a common spindle cell lesion of the H&N. | |||
==Verrucous squamous cell carcinoma== | ==Verrucous squamous cell carcinoma== | ||
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==Spindle cell squamous carcinoma== | ==Spindle cell squamous carcinoma== | ||
* | ===General=== | ||
*Common spindle cell lesion of the head and neck. | |||
===Microscopic=== | |||
* | Feature: | ||
* | *Histomorphologic key to the diagnosis: finding a component of conventional squamous cell carcinoma. | ||
*Malignant spindle cell neoplasm. | |||
DDx: | DDx: | ||
*Spindle cell [[melanoma]]. | *Spindle cell [[melanoma]]. | ||
*Mesenchymal neoplasm. | *Mesenchymal neoplasm. | ||
===IHC=== | |||
*Typically keratin -ve. | |||
*p63 +ve. | |||
==Basaloid squamous cell carcinoma== | ==Basaloid squamous cell carcinoma== | ||