Difference between revisions of "Splenic hamartoma"
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==IHC== | ==IHC== | ||
Features:<ref name=pmid19123729>{{Cite journal | last1 = Lee | first1 = H. | last2 = Maeda | first2 = K. | title = Hamartoma of the spleen. | journal = Arch Pathol Lab Med | volume = 133 | issue = 1 | pages = 147-51 | month = Jan | year = 2009 | doi = 10.1043/1543-2165-133.1.147 | PMID = 19123729 }} | Features: | ||
</ref> | *CD8 +ve endothelial cells.<ref name=pmid19123729>{{Cite journal | last1 = Lee | first1 = H. | last2 = Maeda | first2 = K. | title = Hamartoma of the spleen. | journal = Arch Pathol Lab Med | volume = 133 | issue = 1 | pages = 147-51 | month = Jan | year = 2009 | doi = 10.1043/1543-2165-133.1.147 | PMID = 19123729 }}</ref> | ||
* | *Factor VIII +ve (diffuse intense).<ref name=pmid15735864>{{Cite journal | last1 = Ali | first1 = TZ. | last2 = Beyer | first2 = G. | last3 = Taylor | first3 = M. | last4 = Volpe | first4 = C. | last5 = Papadimitriou | first5 = JC. | title = Splenic hamartoma: immunohistochemical and ultrastructural profile of two cases. | journal = Int J Surg Pathol | volume = 13 | issue = 1 | pages = 103-11 | month = Jan | year = 2005 | doi = | PMID = 15735864 }}</ref> | ||
**Background spleen -ve. | |||
*CD31 -ve.<ref name=pmid15735864/> | |||
**Background spleen +ve. | |||
==See also== | ==See also== | ||
Revision as of 20:40, 8 April 2014
Splenic hamartoma, also hamartoma of the spleen, is an uncommon benign lesion of the spleen.
General
Gross
- Red lesion.
- Well-circumscribed.
Image
Splenic hamartoma. (WC)
Microscopic
Features:[3]
- Variable size irregular vascular channels
- Red pulp-like disorganized stroma
- +/-Lymphoid follicles.
Images
Splenic hamartoma - very low mag. (WC)
Splenic hamartoma - intermed. mag. (WC)
Splenic hamartoma - very high mag. (WC)
IHC
Features:
- CD8 +ve endothelial cells.[3]
- Factor VIII +ve (diffuse intense).[4]
- Background spleen -ve.
- CD31 -ve.[4]
- Background spleen +ve.
See also
References
- ↑ Sankar, S.; Thanka, J.; Jagdishchandrabose, S.; Rajendran, S.. "Splenic hamartoma: a rare vascular space occupying lesion of the spleen.". Indian J Pathol Microbiol 54 (1): 223-5. doi:10.4103/0377-4929.77416. PMID 21393931.
- ↑ Tatekawa, Y.; Kanehiro, H.; Nakajima, Y. (Sep 2007). "Laparoscopic extirpation of splenic hamartoma.". Pediatr Surg Int 23 (9): 911-4. doi:10.1007/s00383-007-1902-1. PMID 17364201.
- ↑ 3.0 3.1 Lee, H.; Maeda, K. (Jan 2009). "Hamartoma of the spleen.". Arch Pathol Lab Med 133 (1): 147-51. doi:10.1043/1543-2165-133.1.147. PMID 19123729.
- ↑ 4.0 4.1 Ali, TZ.; Beyer, G.; Taylor, M.; Volpe, C.; Papadimitriou, JC. (Jan 2005). "Splenic hamartoma: immunohistochemical and ultrastructural profile of two cases.". Int J Surg Pathol 13 (1): 103-11. PMID 15735864.