Difference between revisions of "Spleen"
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(→IHC: more) |
(→Splenic hamartoma: +splenic infarct) |
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*CD8 +ve endothelial cells. | *CD8 +ve endothelial cells. | ||
==Splenic infarct== | |||
*[[AKA]] ''splenic infarction''. | |||
*[[AKA]] ''infarction of the spleen''. | |||
===General=== | |||
Classic textbook causes:<ref name=pmid20928991>{{Cite journal | last1 = Lawrence | first1 = YR. | last2 = Pokroy | first2 = R. | last3 = Berlowitz | first3 = D. | last4 = Aharoni | first4 = D. | last5 = Hain | first5 = D. | last6 = Breuer | first6 = GS. | last7 = Osler | first7 = W. | title = Splenic infarction: an update on William Osler's observations. | journal = Isr Med Assoc J | volume = 12 | issue = 6 | pages = 362-5 | month = Jun | year = 2010 | doi = | PMID = 20928991 | URL = http://www.ima.org.il/imaj/dynamic/web/ArtFromPubmed.asp?year=2010&month=06&page=362 }}</ref> | |||
*Septic embolus due to [[bacterial endocarditis]]. | |||
*[[Sickle cell disease]]. | |||
Usual causes:<ref name=pmid20928991/> | |||
*Hematologic malignancy. | |||
*Intracardiac thrombus. | |||
*Bacterial endocarditis. | |||
Clinical:<ref name=pmid20928991/> | |||
*Left upper quadrant pain ~ 1/3 of cases. | |||
*Fever ~ 1/3 of cases. | |||
*Leukocytosis ~ 1/2 of cases. | |||
===Gross=== | |||
*Classically wedge-shaped; triangular on section. | |||
**The base of the triangle runs along the surface. | |||
**The apex points to the obstructed vessel that lead to the infarct. | |||
===Microscopic=== | |||
:''See [[necrosis]]''. | |||
=Weird stuff= | =Weird stuff= | ||