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Difference between revisions of "Soft tissue lesions"
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→Tumours of uncertain differentiation
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=Tumours of uncertain differentiation= | =Tumours of uncertain differentiation= | ||
==Extrarenal malignant rhabdoid tumour== | |||
*Essentially identical to ''renal malignant rhabdoid tumour''.<ref name=Ref_WMSP627>{{Ref WMSP|627}}</ref> | |||
===General=== | |||
*Usu. children < 2 years old. | |||
*Very poor prognosis. | |||
*In the CNS it is known as ''[[atypical teratoid-rhabdoid tumour]]''.<ref name=Ref_WMSP627>{{Ref WMSP|627}}</ref> | |||
===Microscopic=== | |||
Features:<ref name=Ref_WMSP627>{{Ref WMSP|627}}</ref> | |||
*Variable architecture. | |||
*Round cells. | |||
*Eccentric vesicular nucleus. | |||
*Prominent [[nucleolus]] -- '''key feature'''. | |||
===IHC=== | |||
*INI1 (SMARCB1) -ve. | |||
**AKA BAF47. | |||
==Ewing sarcoma/PNET== | ==Ewing sarcoma/PNET== | ||
{{Main|Ewing sarcoma}} | {{Main|Ewing sarcoma}} | ||