Difference between revisions of "Small round cell tumours"
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==Tabular comparison== | ==Tabular comparison== | ||
Adapted from Thorner:<ref>PST. 14 February 2011.</ref> | |||
{| class="wikitable" | {| class="wikitable" | ||
| '''Tumour''' | | '''Tumour''' | ||
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|- | |- | ||
| Hepatoblastoma | | Hepatoblastoma | ||
| | | fetal hepatocytes (~ 1:3 NC ratio, eosinophilic cytoplasm) | ||
| liver | | liver | ||
| AFP | | AFP | ||
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| Nephroblastoma (Wilms tumour) | | Nephroblastoma (Wilms tumour) | ||
| triphasic - (1) blue cells (blastema), (2) spindle cells (stroma), (3) tubular structures (epithelial) | | triphasic - (1) blue cells (blastema), (2) spindle cells (stroma), (3) tubular structures (epithelial) | ||
| kidney | | kidney lesion, various syndromes | ||
| WT-1+ | | WT-1+ | ||
|- | |- | ||
| Retinoblastoma | | Retinoblastoma | ||
| | | Flexner-Wintersteiner rosette (rosette with empty centre (donut hole))<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref> | ||
| eye | | eye lesion; +/-RB1 gene mutations (familial) | ||
| | | | ||
|- | |- | ||
| Medulloblastoma | | Medulloblastoma | ||
| | | Homer-Wright rosettes (rosette with a meshwork of fibers (neuropil) at the centre)<ref name=pmid16551982>{{cite journal |author=Wippold FJ, Perry A |title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes |journal=AJNR Am J Neuroradiol |volume=27 |issue=3 |pages=488–92 |year=2006 |month=March |pmid=16551982 |doi= |url=}}</ref> | ||
| | | +/-nevoid basal cell carcinoma syndrome | ||
| | | | ||
|- | |- | ||