Difference between revisions of "Small round cell tumours"

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Small round cell tumours (view source)

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Memory device: 4 -blastomas (hepato-, neuro-, nephro-, retino-), PNET/Ewing sarcoma (medulloblastoma), LADSSS (lymphoma, alveolar rhabdomyosarcoma, DSRCT, small cell carcinoma, small cell osteosarcoma, synovial sarcoma).
Memory device: 4 -blastomas (hepato-, neuro-, nephro-, retino-), PNET/Ewing sarcoma (medulloblastoma), LADSSS (lymphoma, alveolar rhabdomyosarcoma, DSRCT, small cell carcinoma, small cell osteosarcoma, synovial sarcoma).
===A long DDx of small blue cell tumours===
{| class="wikitable sortable"
! Tumour
! Group
! Notes/comments
|-
| [[Melanoma]]
| melanoma
| 
|-
| [[PEComa]]
| mesenchymal lesion
| 
|-
| Carcinoma not otherwise specified
| carcinoma
| 
|-
| [[Small cell carcinoma]]
| carcinoma
| 
|-
| [[Merkel cell carcinoma]]
| carcinoma
| 
|-
| [[Islet cell tumour / carcinoid]]
| carcinoma
| 
|-
| [[Medullary thyroid carcinoma]]
| carcinoma
| 
|-
| [[Desmoplastic small cell tumour]]
| sarcoma
| 
|-
| [[Polyphenotypic small cell tumour]]
| other
| 
|-
| [[Papillary-cystic tumor of pancreas]]
| other
| 
|-
| [[Pancreatoblastoma]]
| other
| 
|-
| [[Acinar cell carcinoma]]
| carcinoma
| 
|-
| [[Adenoid cystic carcinoma]]
| carcinoma
| 
|-
| Cutaneous adnexal tumours ([[spiradenoma]], [[acrospiroma]])
| other
| 
|-
| [[Wilm's tumour]]
| other
| 
|-
| [[Thymoma]]
| epithelial lesion
| 
|-
| [[Metanephric adenoma|Metanephric adenoma of urinary tract]]
| epithelial lesion
| 
|-
| Basaloid carcinoma / [[Basal cell carcinoma]]
| carcinoma
| 
|-
| [[Small cell mesothelioma]]
| carcinoma
| 
|-
| [[Pulmonary blastoma]]
| other
| 
|-
| [[Cutaneous myoepithelioma]]
| epithelial lesion
|<ref>{{Cite journal | last1 = Kutzner| first1 = H.| last2 = Mentzel| first2 = T.| last3 = Kaddu| first3 = S.| last4 = Soares| first4 = LM.| last5 = Sangueza| first5 = OP.| last6 = Requena| first6 = L.| title = Cutaneous myoepithelioma: an under-recognized cutaneous neoplasm composed of myoepithelial cells.| journal = Am J Surg Pathol| volume = 25| issue = 3| pages = 348-55| month = Mar| year = 2001| doi = | PMID = 11224605 }}</ref>
|-
| [[Ewing sarcoma]] / [[PNET]]
| neural tumours
| 
|-
| [[Neuroblastoma]] / [[esthesioneuroblastoma]]
| neural tumours
| 
|-
| [[Sclerosing perineurioma]]
| neural tumours
| 
|-
| [[Schwannoma]]
| neural tumours
| 
|-
| [[Meningioma]]
| neural tumours
| 
|-
| [[Medulloblastoma]]
| neural tumours
| 
|-
| [[Central neurocytoma]]
| neural tumours
| 
|-
| [[Medulloepithelioma]]
| neural tumours
| 
|-
| [[Retinoblastoma]]
| neural tumours
| 
|-
| [[Oligodendroglioma]]
| neural tumours
| 
|-
| [[Pineocytoma]]
| neural tumours
| 
|-
| [[Hemangioblastoma]]
| neural tumours
| may be seen extraneural
|-
| [[Neurogenic sarcoma]]
| neural tumours
| 
|-
| [[Lymphoma]]
| lymphoid
| 
|-
| [[Extramedullary leukemia]]
| lymphoid
| 
|-
| [[Plasma cell myeloma]]
| lymphoid
| 
|-
| [[Mastocytosis]]
| lymphoid
| 
|-
| [[Plasmacytoid dendritic cell tumour]]
| lymphoid
|CD4 +ve, CD56 +ve<ref name=pmid16160468>{{Cite journal | last1 = Reichard| first1 = KK.| last2 = Burks| first2 = EJ.| last3 = Foucar| first3 = MK.| last4 = Wilson| first4 = CS.| last5 = Viswanatha| first5 = DS.| last6 = Hozier| first6 = JC.| last7 = Larson| first7 = RS.| title = CD4(+) CD56(+) lineage-negative malignancies are rare tumors of plasmacytoid dendritic cells.| journal = Am J Surg Pathol| volume = 29| issue = 10| pages = 1274-83| month = Oct| year = 2005| doi = | PMID = 16160468 }}</ref>
|-
| [[Granuloma annulare]]
| histiocytic lesion
| 
|-
| [[Seminoma]]
| germ cell tumour
| degenerative cases
|-
| [[Granulosa cell tumors]]
| sex cord tumour
| 
|-
| [[Gynandroblastoma]]
| sex cord tumour
| Sertoli cell & granulosa cell
|-
| [[Sertoli-Leydig tumour]]
| sex cord tumour
| 
|-
| [[Endometrial stromal sarcoma]]
| sarcoma
| may be extragenital
|-
| [[Adenosarcoma]]
| sarcoma
| glandular component may not be sampled
|-
| [[Rhabdomyosarcoma]]
| muscle
| 
|-
| Skeletal muscle regeneration
| muscle
| mimics [[rhabdomyosarcoma]]<ref name=pmid9762546>{{Cite journal | last1 = Guillou| first1 = L.| last2 = Coquet| first2 = M.| last3 = Chaubert| first3 = P.| last4 = Coindre| first4 = JM.| title = Skeletal muscle regeneration mimicking rhabdomyosarcoma: a potential diagnostic pitfall.| journal = Histopathology| volume = 33| issue = 2| pages = 136-44| month = Aug| year = 1998| doi = | PMID = 9762546 }}</ref>
|-
| [[Small cell leiomyosarcoma]]
| sarcoma
| 
|-
| [[Small cell osteosarcoma]]
| Chondro-osseous tumours
| 
|-
| [[Mesenchymal chondrosarcoma]]
| Chondro-osseous tumours
| 
|-
| [[Myxoid chondrosarc]]
| Chondro-osseous tumours
| 
|-
| [[Proliferative myositis]]
| muscle
| 
|-
| [[Fetal or genital rhabdomyoma]]
| other
| 
|-
| [[Glomus tumor]]
| other
| 
|-
| [[Glomangiopericytoma]]
| other
| 
|-
| [[Synovial sarcoma]]
| sarcoma
| 
|-
| [[Hemangiopericytoma]]
| soft tissue lesions
| 
|-
| [[Small cell angiosarcoma]]
| vascular lesions
| 
|-
| [[Epithelioid hemangioendothelioma]]
| vascular lesions
| 
|-
| [[Solitary fibrous tumour]]
| soft tissue lesions
| can be myxoid
|-
| [[Myofibroblastoma]]
| soft tissue lesions
| 
|-
| [[Angiomyofibroblastoma]]
| soft tissue lesions
| 
|-
|}


==Microscopic==
==Microscopic==
Michael
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