Difference between revisions of "Sjögren syndrome"

Jump to navigation Jump to search
24 bytes added ,  15:13, 11 April 2013
Line 50: Line 50:
==Microscopic==
==Microscopic==
Features ([[salivary gland]]):<ref name=pmid19323360/>
Features ([[salivary gland]]):<ref name=pmid19323360/>
*Viable [[salivary gland]] (or [[lacrimal gland]]) acini with significant lymphocytic infiltration - '''key feature'''.
*Viable [[salivary gland]] (or [[lacrimal gland]]) acini adjacent to a significant lymphocytic infiltrate - '''key feature'''.
**Plasma cells should not exceed 10% of the inflammatory infiltrate.<ref name=pmid12022353/>
**"Significant" lymphocytic infiltrate: cluster of >= 50 lymphocytes - '''important'''.
**"Significant" infiltrate = cluster of >= 50 lymphocytes - '''important'''.
***Lymphocytes that are perivascular count.<ref name=pmid12022353/>
***Lymphocytes that are perivascular count.<ref name=pmid12022353/>
***May have "benign lymphoepithelial lesion"<ref name=pmid15956090/> - intraepithelial lymphocytes.
***[[Plasma cell]]s should not exceed 10% of the inflammatory infiltrate.<ref name=pmid12022353/>
***May have "benign lymphoepithelial lesions"<ref name=pmid15956090/> - intraepithelial lymphocytes.
*+/-Fibrosis.
*+/-Fibrosis.


48,466

edits

Navigation menu