Difference between revisions of "Sjögren syndrome"
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==General== | ==General== | ||
Clinical: | Clinical - classically: | ||
* | *Women in 50s. | ||
*Dry mouth (xerostomia). | |||
*Dry eyes (xerophthalmia). | |||
Blood work:<ref name=pmid19323360>{{Cite journal | title = Information from your family doctor. Sjögren syndrome. | journal = Am Fam Physician | volume = 79 | issue = 6 | pages = 472 | month = Mar | year = 2009 | doi = | PMID = 19323360 | URL = http://www.aafp.org/afp/2009/0315/p465.html }}</ref> | |||
*ANA +ve. | |||
*Anti-SSA (Ro) +ve. | |||
*Anti-SSB (La) +ve. | |||
==Microscopic== | |||
Features (salivary gland):<ref name=pmid19323360/> | |||
*Lymphocytic infiltration - '''key feature'''. | |||
*+/-Atrophy of salivary gland. | |||
*+/-Fibrosis. | |||
DDx: | |||
*[[MALT lymphoma]]. | |||
==See also== | ==See also== | ||
*[[Systemic lupus erythematosus]]. | *[[Systemic lupus erythematosus]]. | ||
*[[Scleroderma]]. | *[[Scleroderma]]. | ||
==References== | |||
{{Reflist|1}} | |||
[[Category:Clinical]] | [[Category:Clinical]] | ||
Revision as of 04:21, 24 March 2012
Sjögren syndrome, also Sjögren disease, is a disease that keeps rheumatologists busy. Sjögren is also spelled Sjoegren and Sjogren.
General
Clinical - classically:
- Women in 50s.
- Dry mouth (xerostomia).
- Dry eyes (xerophthalmia).
Blood work:[1]
- ANA +ve.
- Anti-SSA (Ro) +ve.
- Anti-SSB (La) +ve.
Microscopic
Features (salivary gland):[1]
- Lymphocytic infiltration - key feature.
- +/-Atrophy of salivary gland.
- +/-Fibrosis.
DDx: