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Difference between revisions of "Sertoli-Leydig cell tumour"
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#*Stromal edema may be prominent | #*Stromal edema may be prominent | ||
# +/- Sarcomatous features (mucinous glands, bone, cartilage). | # +/- Sarcomatous features (mucinous glands, bone, cartilage). | ||
*Growth Patterns: | |||
**Well-differentiated. | |||
Growth Patterns: | ***Hollow or solid tubules of mature Sertoli cells with Leydig cells in the intervening stroma. | ||
**Well-differentiated | **Intermediate (most common). | ||
***Hollow or solid tubules of mature Sertoli cells with Leydig cells in the intervening stroma | ***Jumbled admixture of dark blue Sertoli cells and Leydig cells. | ||
**Intermediate (most common) | ***Lobules comprising sheets of Sertoli cells. | ||
***Jumbled admixture of dark blue Sertoli cells and Leydig cells | |||
***Lobules comprising sheets of Sertoli cells | |||
***Some areas of tubules. | ***Some areas of tubules. | ||
**Poorly differentiated | **Poorly differentiated. | ||
***Masses of malignant spindle cells – sheets of cells can be reminiscent of fibrosarcoma or granulosa cell tumour | ***Masses of malignant spindle cells – sheets of cells can be reminiscent of fibrosarcoma or granulosa cell tumour. | ||
***Tubules may be a very minor element | ***Tubules may be a very minor element. | ||
**With heterologous element | **With heterologous element. | ||
***Mucinous intestinal-type epithelium, cartilage, skeletal muscle | ***Mucinous intestinal-type epithelium, cartilage, skeletal muscle. | ||
***Heterologous elements can also occur with retiform or poorly differentiated tumours | ***Heterologous elements can also occur with retiform or poorly differentiated tumours. | ||
**Retiform | **Retiform. | ||
***Tumour resembles rete testis/ovary with blunt papillae and irregular cleft-like spaces | ***Tumour resembles rete testis/ovary with blunt papillae and irregular cleft-like spaces. | ||
DDx: | DDx: | ||