Serrated polyposis syndrome
Revision as of 00:33, 14 December 2011 by Michael (talk | contribs) (→WHO definition: replace ref.)
Hyperplastic polyposis syndrome is an uncommon condition characterized by the presence of (colonic) hyperplastic polyps, may represent several distinct pathologies and is associated with an increased risk of colorectal carcinoma.[1]
WHO definition
One of the following three:[1]
- >=Five hyperplastic polyps proximal to the sigmoid colon with two of the five >=10 mm.
- One hyperplastic polyps proximal to the sigmoid colon, in someone with a first degree relative with the syndrome.
- >30 hyperplastic polyps through-out the colon, i.e. not all can be rectal polyps.
- One source[2] suggests it ought to be >=20 HPs.
See also
References
- ↑ 1.0 1.1 Huang, CS.; Farraye, FA.; Yang, S.; O'Brien, MJ. (Feb 2011). "The clinical significance of serrated polyps.". Am J Gastroenterol 106 (2): 229-40; quiz 241. doi:10.1038/ajg.2010.429. PMID 21045813.
- ↑ Rosty, C.; Parry, S.; Young, JP. (2011). "Serrated polyposis: an enigmatic model of colorectal cancer predisposition.". Patholog Res Int 2011: 157073. doi:10.4061/2011/157073. PMID 21660283.