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Serous cystadenoma of the pancreas (view source)
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'''Serous cystadenoma of the pancreas''' is a benign cystic lesion of the pancreas. It may be seen in [[von Hippel-Lindau disease]]. | |||
It is also known as '''serous microcystic adenoma''',<ref name=Ref_Sternberg4_1630>{{Ref Sternberg4|1630}}</ref> and '''pancreatic serous cystadenoma'''. | |||
==General== | |||
*1-2% of all exocrine pancreatic tumours. | |||
*Female > male. | |||
*Mean age 66 years. | |||
*Truly benign with no malignant potenial. | |||
*May be part of [[von Hippel-Lindau syndrome]]. | |||
Management: | |||
*Observe or resect. | |||
==Gross== | |||
Features: | |||
*Classically has a characteristic central scar.<ref name=pmid15888617>{{cite journal |author=Kim YH, Saini S, Sahani D, Hahn PF, Mueller PR, Auh YH |title=Imaging diagnosis of cystic pancreatic lesions: pseudocyst versus nonpseudocyst |journal=Radiographics |volume=25 |issue=3 |pages=671–85 |year=2005 |pmid=15888617 |doi=10.1148/rg.253045104 |url=http://radiographics.rsna.org/content/25/3/671.abstract}}</ref> | |||
*Bosulated surface. | |||
*Lobulated. | |||
*No (macroscopic) cysts apparent on gross. | |||
*Location: 50-70% occur in the body and tail. | |||
*Size: average size 11 cm. | |||
Radiologic appearance: | |||
*Honey comb-like appearance. | |||
*Well demarcated border - may be described as a "coin lesion". | |||
Image: | |||
*[http://www.joplink.net/prev/200905/25_fig06.jpg Serous microcystic adenoma (joplink.net)].<ref name=pmid19454830>{{Cite journal | last1 = Vernadakis | first1 = S. | last2 = Kaiser | first2 = GM. | last3 = Christodoulou | first3 = E. | last4 = Mathe | first4 = Z. | last5 = Troullinakis | first5 = M. | last6 = Bankfalvi | first6 = A. | last7 = Paul | first7 = A. | title = Enormous serous microcystic adenoma of the pancreas. | journal = JOP | volume = 10 | issue = 3 | pages = 332-4 | month = | year = 2009 | doi = | PMID = 19454830 |URL = http://www.joplink.net/prev/200905/25.html }}</ref> | |||
==Microscopic== | |||
Features: | |||
*Cystic spaces lined by cuboidal cells. | |||
**Glycogen rich. | |||
**Cilia. (???) | |||
DDx: | |||
*[[Renal cell carcinoma]]. | |||
*[[Lymphangioma]]. | |||
*[[Hemangioma]]. | |||
*Oligocystic mucinous cystic tumors and pseudocysts. | |||
**Have mucin; PAS-D could be used to demonstrate its presence. | |||
Notes: | |||
*Serous adenoma may coexist with aggressive tumours. | |||
===Images=== | |||
<gallery> | |||
Image:Pancreatic_serous_cystadenoma_-_low_mag.jpg | PSC - low mag. (WC) | |||
Image:Pancreatic_serous_cystadenoma_-_intermed_mag.jpg | PSC - intermed. mag. (WC) | |||
Image:Pancreatic_serous_cystadenoma_-_high_mag.jpg | PSC - high mag. (WC) | |||
Image:Pancreatic_serous_cystadenoma_-_very_high_mag.jpg | PSC - very high mag. (WC) | |||
</gallery> | |||
==Stains== | |||
*PAS +ve. | |||
*PASD -ve. | |||
==See also== | |||
*[[Pancreas]]. | |||
*[[Serous cystadenoma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Pancreas]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||