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Difference between revisions of "Seminoma"
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(ITGCN --> GCNIS) |
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| Micro = fried egg-like cells (clear or eosinophilic cytoplasm, central nucleus), lymphocytic infiltrate (common), +/-[[syncytiotrophoblast]]s (rare), +/-granulomas (uncommon) | | Micro = fried egg-like cells (clear or eosinophilic cytoplasm, central nucleus), lymphocytic infiltrate (common), +/-[[syncytiotrophoblast]]s (rare), +/-granulomas (uncommon) | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[embryonal carcinoma]], [[GCNIS]] | | LMDDx = [[embryonal carcinoma]], [[GCNIS]], [[mixed germ cell tumour]], [[granulomatous orchitis]], [[testicular scar]], [[atrophic testis]] | ||
| Stains = | | Stains = | ||
| IHC = OCT3 +ve, CD117 +ve, CD30 -ve | | IHC = OCT3 +ve, CD117 +ve, CD30 -ve | ||
| Line 45: | Line 45: | ||
===Epidemiology & etiology=== | ===Epidemiology & etiology=== | ||
*Arises from ''[[germ cell neoplasia in situ]]'' ( | *Arises from ''[[germ cell neoplasia in situ]]'', abbreviated ''GCNIS'' (previously known as ''intratubular germ cell neoplasia''). | ||
==Gross== | ==Gross== | ||