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===Images=== | ===Images=== | ||
<gallery> | <gallery> | ||
Image:Mammary_analogue_secretory_carcinoma_(mammaglobin_immunohistochemstry,_medium_power).jpg | MASC - | Image:Mammary_analogue_secretory_carcinoma_(mammaglobin_immunohistochemstry,_medium_power).jpg | MASC - mammaglobin. (WC/NormanDy) | ||
Image:Mammary_analogue_secretory_carcinoma_(S100immunohistochemstry,_low_power).jpg | MASC - S-100. (WC/NormanDy) | Image:Mammary_analogue_secretory_carcinoma_(S100immunohistochemstry,_low_power).jpg | MASC - S-100. (WC/NormanDy) | ||
</gallery> | </gallery> | ||
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Note: | Note: | ||
*The translocation seen in [[secretory breast carcinoma]], [[congenital-infantile fibrosarcoma]] and [[mesoblastic nephroma]]. | *The translocation seen in [[secretory breast carcinoma]], [[congenital-infantile fibrosarcoma]] and [[mesoblastic nephroma]]. | ||
==Sign out== | |||
<pre> | |||
Right Parotid Lesion, Core Biopsy: | |||
- SECRETORY CARCINOMA of the salivary gland, see comment. | |||
Comment: | |||
Secretory carcinoma of the salivary gland was previously known as "mammary analogue secretory carcinoma" (MASC). | |||
The tumour stains as follows: | |||
POSITIVE: CK7 (strong, diffuse), mammaglobin (strong, diffuse), S100 (moderate, patchy), mucin (focal). | |||
NEGATIVE: p63. | |||
NTRK testing was ordered; the results will be reported in an addendum. | |||
</pre> | |||
===Micro=== | |||
The sections show a cohesive tumor with moderate amphophilic cytoplasm and vacuolation. The vacuolation is focally prominent. Nucleoli are inconspicuous. Poorly formed glands are present. Keratinization is absent. | |||
==See also== | ==See also== |
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