Difference between revisions of "Secretory carcinoma of the salivary gland"
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'''Mammary analogue secretory carcinoma''', | '''Mammary analogue secretory carcinoma''', abbreviated '''MASC''', is a newly described [[malignant]] [[salivary gland]] tumour.<ref name=pmid22127547>{{Cite journal | last1 = Lei | first1 = Y. | last2 = Chiosea | first2 = SI. | title = Re-evaluating historic cohort of salivary acinic cell carcinoma with new diagnostic tools. | journal = Head Neck Pathol | volume = 6 | issue = 2 | pages = 166-70 | month = Jun | year = 2012 | doi = 10.1007/s12105-011-0312-9 | PMID = 22127547 }}</ref> | ||
==General== | ==General== | ||
Revision as of 01:20, 14 February 2014
Mammary analogue secretory carcinoma, abbreviated MASC, is a newly described malignant salivary gland tumour.[1]
General
- Described in pediatric patient.[2]
Microscopic
Features:
- Serous cells. (???)
DDx:
- Acinic cell carcinoma - very closely mimics.
- Mucoepidermoid carcinoma.
Images
Molecular
- t(12;15)(p13;q25)
- Fusion of the genes ETV6 and NTRK3.[1]
Note:
- The translocation seen in congenital-infantile fibrosarcoma.
See also
References
- ↑ 1.0 1.1 1.2 Lei, Y.; Chiosea, SI. (Jun 2012). "Re-evaluating historic cohort of salivary acinic cell carcinoma with new diagnostic tools.". Head Neck Pathol 6 (2): 166-70. doi:10.1007/s12105-011-0312-9. PMID 22127547.
- ↑ Rastatter, JC.; Jatana, KR.; Jennings, LJ.; Melin-Aldana, H. (Mar 2012). "Mammary analogue secretory carcinoma of the parotid gland in a pediatric patient.". Otolaryngol Head Neck Surg 146 (3): 514-5. doi:10.1177/0194599811419044. PMID 21873597.