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Difference between revisions of "Seborrheic keratosis"
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==Gross== | ==Gross== | ||
[[Image:Seborrheic keratosis on human back.jpg|thumb|right|Clinical image showing a large number of SKs (Leser–Trélat sign). (WC/Heilman)]] | |||
*"Stuck-on" appearance - raised lesion. | *"Stuck-on" appearance - raised lesion. | ||
==Microscopic== | ==Microscopic== | ||
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*[[Basal cell carcinoma]], fibroepitheliomatous pattern - esp. reticulated SK. | *[[Basal cell carcinoma]], fibroepitheliomatous pattern - esp. reticulated SK. | ||
*[[Melanocytic nevus]]. | *[[Melanocytic nevus]]. | ||
*[[Condyloma acuminatum]] - may have horn cysts, more probable than SK in the genital area. | *[[Condyloma acuminatum]] - may have horn cysts, more probable than SK in the genital area.<ref name=pmid7978069>{{Cite journal | last1 = Li | first1 = J. | last2 = Ackerman | first2 = AB. | title = "Seborrheic keratoses" that contain human papillomavirus are condylomata acuminata. | journal = Am J Dermatopathol | volume = 16 | issue = 4 | pages = 398-405; discussion 406-8 | month = Aug | year = 1994 | doi = | PMID = 7978069 }}</ref> | ||
*[[Inverted follicular keratosis]] - predominantly endophytic growth pattern, may be considered a variant of seborrheic keratosis.<ref name=Ref_Derm341>{{Ref Derm|341}}</ref> | *[[Inverted follicular keratosis]] - predominantly endophytic growth pattern, may be considered a variant of seborrheic keratosis.<ref name=Ref_Derm341>{{Ref Derm|341}}</ref> | ||
*Collision with another lesion. | *Collision with another lesion. | ||
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*[[Acanthosis nigricans]] - site important. | *[[Acanthosis nigricans]] - site important. | ||
*[[Fibroepithelial polyp]], epithelial type - may have abundant compact keratin, lack horn cysts. | *[[Fibroepithelial polyp]], epithelial type - may have abundant compact keratin, lack horn cysts. | ||
*[[Eccrine poroma]] - lack horn cysts. | |||
===Images=== | ===Images=== | ||
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Image: Seborrheic keratosis - high mag.jpg | SK - high mag. (WC) | Image: Seborrheic keratosis - high mag.jpg | SK - high mag. (WC) | ||
</gallery> | </gallery> | ||
www | ====www==== | ||
*[http://www.dermatlas.org/derm/IndexDisplay.cfm?ImageID=-1985374774 Seborrheic keratosis - high mag. (dermatlas.org)]. | *[http://www.dermatlas.org/derm/IndexDisplay.cfm?ImageID=-1985374774 Seborrheic keratosis - high mag. (dermatlas.org)]. | ||
*[http://www.dermatlas.org/derm/IndexDisplay.cfm?ImageID=-1880960893 Seborrheic keratosis - low mag. (dermatlas.org)]. | *[http://www.dermatlas.org/derm/IndexDisplay.cfm?ImageID=-1880960893 Seborrheic keratosis - low mag. (dermatlas.org)]. | ||
*[http:// | *[http://ispub.com/IJD/7/2/7627 Gallery of SK variants (ispub.com)].<ref>{{Cite journal | last1 = Sarma | first1 = DP. | last2 = Repertinger | first2 = S. | title = Seborrheic Keratosis: A Pictorial Review of the Histopathologic Variations. | journal = The Internet Journal of Dermatology| volume = 7 | issue = 2 | pages = | month = | year = | doi = | PMID = |URL = http://ispub.com/IJD/7/2/7627 }}</ref> | ||
*[http:// | *[http://ispub.com/IJD/6/2/3323 Acantholytic SK (ispub.com)].<ref>{{Cite journal | last1 = Wang | first1 = J | last2 = Wang | first2 = B | last3 = Shehan | first3 = J | last4 = Sarma | first4 = D | title = Acantholytic Seborrheic Keratosis | journal = The Internet Journal of Dermatology. | volume = 6 | issue = 2 | pages = | month = | year = 2007 | doi = | PMID = | PMC = | url = http://print.ispub.com/api/0/ispub-article/3323 }}</ref> | ||
===Histologic subtypes=== | ===Histologic subtypes=== | ||
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==Sign out== | ==Sign out== | ||
<pre> | |||
Skin Lesion, Left Lower Leg, Excision: | |||
- Seborrheic keratosis, completely excised. | |||
- Solar elastosis. | |||
</pre> | |||
<pre> | |||
Skin Lesion (Submitted "Seborrheic Keratosis"), Right Back, Excision: | |||
- Extensively fragmented bland superficial squamous epithelium with | |||
horn cysts and keratineous material, compatible with impression of | |||
seborrheic keratosis; deeper lesion cannot be excluded. | |||
</pre> | |||
===Block letters=== | |||
<pre> | <pre> | ||
SKIN LESION, MID BACK, BIOPSY: | SKIN LESION, MID BACK, BIOPSY: | ||
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There are no melanocytic nests. There is no apparent solar elastosis. There is a moderate lymphohistiocytic dermal infiltrate. There is minimal basal atypia. Mitotic activity is not readily apparent. | There are no melanocytic nests. There is no apparent solar elastosis. There is a moderate lymphohistiocytic dermal infiltrate. There is minimal basal atypia. Mitotic activity is not readily apparent. | ||
====Stucco keratosis==== | |||
The sections show skin with pointed papillomatous projections and hyperkeratosis. | |||
There is no basal nuclear atypia, and there are no melanocytic nests. Mitotic activity is | |||
not apparent. There is minimal dermal inflammation. Solar elastosis is present. | |||
The lesion is excised in the plane of section. | |||
Note: | |||
*Signed out as ''seborrheic keratosis, early''. | |||
==See also== | ==See also== | ||