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*Subchondral [[necrosis]] of bone - '''key feature'''. | *Subchondral [[necrosis]] of bone - '''key feature'''. | ||
**Loss of osteocytes within the bony trabeculae. | **Loss of osteocytes within the bony trabeculae. | ||
*Bone marrow cavity fibrosis with loss of adipocytes (reactive process). | *Reactive [[woven bone]]: | ||
**Thickened trabeculae. | |||
**Increased numbers of osteoblasts and osteoclasts. | |||
*Bone marrow cavity fibrosis with small blood vessels and loss of adipocytes (reactive process). | |||
Note: | Note: | ||
*Histologically, considered a cousin of [[avascular necrosis of the femoral head]].<ref name= | *Histologically, ''Schmorl's node'' is considered a cousin of [[avascular necrosis of the femoral head]].<ref name=pmid12931811/> | ||
==Sign out== | |||
<pre> | |||
LESION, L4 VERTEBRA, BIOPSY: | |||
- BENIGN BONE AND BONE MARROW. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
===Micro=== | |||
The sections show woven bone with slightly thickened bony trabeculae. Bone with some empty | |||
lacunae is seen focally. A small amount of benign fibrotic tissue with small blood vessels | |||
is present. The bone marrow present has all three lineages. No atypical cells are apparent. | |||
==See also== | ==See also== |
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