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Difference between revisions of "Sarcoma with CIC-rearrangement"
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Sarcoma with CIC-rearrangement (view source)
Revision as of 18:40, 17 February 2022
, 18:40, 17 February 2022→IHC
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**Irregular spacing of cells. | **Irregular spacing of cells. | ||
**+/-Big nucleoli. | **+/-Big nucleoli. | ||
<gallery> | |||
File:CIC-DUX-sarcoma.jpg | CIC-DUX rearranged sarcoma in the CNS (WC/jensflorian) | |||
</gallery> | |||
DDx: | DDx: | ||
| Line 68: | Line 72: | ||
*ERG +ve. | *ERG +ve. | ||
*FLI-1 +ve. | *FLI-1 +ve. | ||
*CD56 +ve/-ve (5 +ve of 9<ref name=pmid28197724>{{cite journal |authors=Yamada Y, Kuda M, Kohashi K, Yamamoto H, Takemoto J, Ishii T, Iura K, Maekawa A, Bekki H, Ito T, Otsuka H, Kuroda M, Honda Y, Sumiyoshi S, Inoue T, Kinoshita N, Nishida A, Yamashita K, Ito I, Komune S, Taguchi T, Iwamoto Y, Oda Y |title=Histological and immunohistochemical characteristics of undifferentiated small round cell sarcomas associated with CIC-DUX4 and BCOR-CCNB3 fusion genes |journal=Virchows Arch |volume=470 |issue=4 |pages=373–380 |date=April 2017 |pmid=28197724 |doi=10.1007/s00428-017-2072-8 |url=}}</ref>). | |||
==Molecular== | ==Molecular== | ||