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Difference between revisions of "Sarcoma with CIC-rearrangement"
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Sarcoma with CIC-rearrangement (view source)
Revision as of 01:08, 20 March 2019
, 01:08, 20 March 2019→Molecular
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==Molecular== | ==Molecular== | ||
*t(4;19)(q35;q13.1).<ref name=pmid22072439>{{Cite journal | last1 = Italiano | first1 = A. | last2 = Sung | first2 = YS. | last3 = Zhang | first3 = L. | last4 = Singer | first4 = S. | last5 = Maki | first5 = RG. | last6 = Coindre | first6 = JM. | last7 = Antonescu | first7 = CR. | title = High prevalence of CIC fusion with double-homeobox (DUX4) transcription factors in EWSR1-negative undifferentiated small blue round cell sarcomas. | journal = Genes Chromosomes Cancer | volume = 51 | issue = 3 | pages = 207-18 | month = Mar | year = 2012 | doi = 10.1002/gcc.20945 | PMID = 22072439 }}</ref> | *Rearrangement of CIC gene, e.g. t(4;19)(q35;q13.1).<ref name=pmid22072439>{{Cite journal | last1 = Italiano | first1 = A. | last2 = Sung | first2 = YS. | last3 = Zhang | first3 = L. | last4 = Singer | first4 = S. | last5 = Maki | first5 = RG. | last6 = Coindre | first6 = JM. | last7 = Antonescu | first7 = CR. | title = High prevalence of CIC fusion with double-homeobox (DUX4) transcription factors in EWSR1-negative undifferentiated small blue round cell sarcomas. | journal = Genes Chromosomes Cancer | volume = 51 | issue = 3 | pages = 207-18 | month = Mar | year = 2012 | doi = 10.1002/gcc.20945 | PMID = 22072439 }}</ref>; CIC-DUX4 fusion. | ||
*EWSR1 FISH negative. | *EWSR1 FISH negative. | ||