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Difference between revisions of "Salivary glands"
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→IHC overview
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| [[basal cell adenoma]] | | [[basal cell adenoma]] | ||
| exclusively oral cavity, 80% in upper lip; IHC: p63- | | exclusively oral cavity, 80% in upper lip; IHC: p63- | ||
| - | | [[Image:Canalicular_adenoma_--_high_mag.jpg | thumb | center |150px| CA. (WC)]] | ||
|- | |- | ||
|[[Sialoblastoma]] | |[[Sialoblastoma]] | ||
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==IHC overview== | ==IHC overview== | ||
General: | General: | ||
*Usually has limited value. | *Usually has limited value. <!--as per Ilan Weinreb--> | ||
Overview: | |||
*Luminal markers: [[CK7]], [[CK19]], CAM5.2 (LMWK). | *Luminal markers: [[CK7]], [[CK19]], CAM5.2 (LMWK). | ||
*Basal markers: p63, HMWK, CK14. | *Basal markers: p63, HMWK, CK14. | ||
| Line 237: | Line 237: | ||
Notes: | Notes: | ||
*p63 and S-100 are sometimes call myoepithelial. | *p63 and S-100 are sometimes call myoepithelial. | ||
Specifics: | |||
*Calponin, S-100, Ki-67 may be useful as per Nagao ''et al.''<ref>{{Cite journal | last1 = Nagao | first1 = T. | last2 = Sato | first2 = E. | last3 = Inoue | first3 = R. | last4 = Oshiro | first4 = H. | last5 = H Takahashi | first5 = R. | last6 = Nagai | first6 = T. | last7 = Yoshida | first7 = M. | last8 = Suzuki | first8 = F. | last9 = Obikane | first9 = H. | title = Immunohistochemical analysis of salivary gland tumors: application for surgical pathology practice. | journal = Acta Histochem Cytochem | volume = 45 | issue = 5 | pages = 269-82 | month = Oct | year = 2012 | doi = 10.1267/ahc.12019 | PMID = 23209336 }}</ref> | |||
=Benign= | =Benign= | ||